chemistry1

JWBK121-FM October 11, 2006 21:10 Char Count= 0 Caution! Read This The information given in this book is believed to be accurate ...

JWBK121-FM October 11, 2006 21:10 Char Count= 0 xxx ...

Addition and condensation reactions 37 +2 H 2 C CHY MeOH, NaOH C NO 2 NO 2 (CH 2 )n C NO 2 NO 2 NO 2 NO 2 YCH 2 CH 2 (CH 2 )n Y ...

1 Synthetic Routes to Aliphatic C-Nitro Functionality 1.1 Introduction The nitro group, whether attached to aromatic or aliphati ...

38 Synthetic Routes to AliphaticC-Nitro alcohols with two or more strong electron-withdrawing groups on theβ-carbon atom to the ...

2 Synthetic Routes to AliphaticC-Nitro functionalized compounds, of which some find application as energetic plasticizers and po ...

Addition and condensation reactions 39 Table 1.10 Michael 1,4-addition of nitroalkanes and nitramines with 2-nitroacetates (nitr ...

Addition of nitric acid, nitrogen oxides 3 centres which are only nitrated with difficulty. With increased temperature these rea ...

40 Synthetic Routes to AliphaticC-Nitro Frankel^258 synthesized 2-nitro-3-acetoxy-1-propene (139) by heating 1,3-diacetoxy-2- ni ...

4 Synthetic Routes to AliphaticC-Nitro The reaction of fuming nitric acid with 2-methyl-2-butene (3) is reported to yield 2-meth ...

Addition and condensation reactions 41 form the 1,1-dinitroethane anion (149) (Pathway 1). More unusual is the second reaction w ...

Addition of nitric acid, nitrogen oxides 5 1,2-Dinitroethane and 1,2-dinitrocyclohexane can be formed in this way from the corre ...

42 Synthetic Routes to AliphaticC-Nitro CCH 2 OAc NO 2 Br NO 2 CCH 2 OAc O 2 N KO 2 N NO 2 NO 2 H H NO 2 NO 2 H H H 2 SO 4 CCH 2 ...

6 Synthetic Routes to AliphaticC-Nitro At temperatures between 0◦C and 25◦C thevic-dinitrate ester is often observed in the prod ...

Addition and condensation reactions 43 1.10.3 Mannich reaction R 2 NCH 2 + H 2 O (Eq. 1.4) R 2 NCH 2 C(NO 2 ) 3 (Eq. 1.5) R 2 NC ...

Halide displacement 7 treatment of the resultingβ-nitroalkyl bromide with triethylamine, is also a general route to α-nitroalken ...

44 Synthetic Routes to AliphaticC-Nitro Frankel and Klager^289 have reported using the Mannich reaction for the condensation of ...

8 Synthetic Routes to AliphaticC-Nitro XCH 2 (CH 2 )nCH 2 XO 2 NCH 2 (CH 2 )nCH 2 NO 2 NaNO 2 , DMF phloroglucinol, (NH 2 ) 2 CO ...

Addition and condensation reactions 45 Formaldehyde is the most important aldehyde used in Henry reactions in relation to ener- ...

46 Synthetic Routes to AliphaticC-Nitro derivatives are much safer to store than the parent nitronate salts and are readily conv ...