Infectious Agents Associated Cancers Epidemiology and Molecular Biology
8 References de Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D et al (2012) Global burden of cancers attributable ...
9 Andersson J (2000) An overview of Epstein-Barr virus: from discovery to future directions for treatment and prevention. Herpe ...
© Springer Nature Singapore Pte Ltd. 2017 11 Q. Cai et al. (eds.), Infectious Agents Associated Cancers: Epidemiology and Molecu ...
12 mortality [ 1 ]. Hepatocellular carcinoma (HCC) is the most common type of liver cancer. The majority of HCC is associated wi ...
13 2.2.1 Long-Lasting Infection and High Levels of Viral Replication Long-lasting chronic HBV infection is associated with HCC d ...
14 not required for HBV replication. Nevertheless, DNA integration into the genomes of host hepatocytes likely contributes to on ...
15 reading frame overlaps the BCP/preC region, some mutations may affect HBx expression or activity. HBV mutants with point muta ...
16 promoting mitochondria membrane depolarization or Ca2+ accumulation in mito- chondria [ 59 , 60 ]. HBx may also promote stemn ...
17 2.4 Conclusions HCC will continue to be one of the major cancers worldwide as chronic HBV infec- tion remains a public health ...
18 Farci P, Niro GA (2012) Clinical features of hepatitis D. Semin Liver Dis 32:228–236 Wang SH, Yeh SH, Lin WH, Wang HY, Chen ...
19 C, Xu J, Kan Z, Dai H, Mao M, Reinhard C, Wang J, Luk JM (2012) Genome-wide survey of recurrent HBV integration in hepatocell ...
20 Knoll S, Furst K, Thomas S, Villanueva Baselga S, Stoll A, Schaefer S, Putzer BM (2011) Dissection of cell context-dependent ...
21 Wang LH, Huang W, Lai MD, Su IJ (2012) Aberrant cyclin A expression and centrosome overduplication induced by hepatitis B vi ...
© Springer Nature Singapore Pte Ltd. 2017 23 Q. Cai et al. (eds.), Infectious Agents Associated Cancers: Epidemiology and Molecu ...
24 are responsible for approximately ∼70% of invasive cervical cancers worldwide [ 4 ]. In contrast with the HR types, the LR HP ...
25 3.3 Molecular Biology It is known that HPVs replicate and assemble exclusively in the nucleus. Virus infects the keratinocyte ...
26 is possible for the virus to remain in a non-detectable, dormant state and then reac- tivate years later [ 18 ]. 3.5 Molecula ...
27 in the United States, primary HPV testing has been recommended only in combina- tion with cytology in primary screening or fo ...
28 with other HR HPV types [ 35 ]. HPV16 and HPV18 viral loads have been reported to be a stronger predictor for the persistence ...
29 evaluate the possibility of de-escalation of radiotherapy doses in the treatment of HPV-associated oropharyngeal cancers [ 46 ...
«
1
2
3
4
5
6
7
8
9
10
»
Free download pdf