Infectious Agents Associated Cancers Epidemiology and Molecular Biology
110 receptors (TLRs), nucleotide-binding oligomerization domain (NOD)-like recep- tors (NLRs), retinoic acid-inducible gene I (R ...
111 inflammasome) undergoes autoactivation via proteolytic cleavage to generate active caspase1. Caspase1 cleaves pro-IL1 and pr ...
112 7.5.4 KSHV-Induced Cellular Metabolic Alterations Cancer cells rely on aerobic glycolysis for their proliferation, in contra ...
113 contributes to cell survival during infection [ 209 ]. Mechanistically, the miRNAs encoded by KSHV target and downregulate t ...
114 phase. p53 controls genomic stability and prevents genomic mutations, and its inac- tivation promotes cell immortalization. ...
115 the promoters of p53 target genes [ 223 ]. Murine double minute 2 (MDM2), a p53 E3 ubiquitin ligase, targets p53 for ubiquit ...
116 models. Therefore, everything we learn from the current experimental system may invite misinterpretation. To better develop ...
117 Beral V et al (1990) Kaposi’s sarcoma among persons with AIDS: a sexually transmitted infection? Lancet 335(8682):123–128 ...
118 Lagunoff M, Ganem D (1997) The structure and coding organization of the genomic termini of Kaposi’s sarcoma-associated herp ...
119 Hladik W et al (2006) Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med 355(13):1331–1338 Aluigi MG e ...
120 Rappocciolo G et al (2008) Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes throug ...
121 Cheng F et al (2015) Screening of the human Kinome identifies MSK1/2-CREB1 as an essential pathway mediating Kaposi’s sarc ...
122 Guasparri I, Keller SA, Cesarman E (2004) KSHV vFLIP is essential for the survival of infected lymphoma cells. J Exp Med 19 ...
123 Liang Y, Ganem D (2003) Lytic but not latent infection by Kaposi’s sarcoma-associated her- pesvirus requires host CSL prote ...
124 Cancian L, Hansen A, Boshoff C (2013) Cellular origin of Kaposi’s sarcoma and Kaposi’s sarcoma- associated herpesvirus-indu ...
125 Felcht M et al (2012) Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. J Clin Inve ...
126 Wu JJ et al (2015) Inhibition of cGAS DNA sensing by a herpesvirus Virion protein. Cell Host Microbe 18(3):333–344 Hanahan ...
127 Uldrick TS et al (2012) Phase II study of bevacizumab in patients with HIV-associated Kaposi’s sarcoma receiving antiretro ...
© Springer Nature Singapore Pte Ltd. 2017 129 Q. Cai et al. (eds.), Infectious Agents Associated Cancers: Epidemiology and Molec ...
130 Thereafter, using an assay for detecting circulating antibodies identified, approxi- mately 80% of the infected patients dev ...
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