Multiphase Bioreactor Design

Figure 8.3 Conversion of solid Ca- maleate to solid Ca-D-malate by permeabilized P. pseudoalcaligenes at 30°C and 250 rpm in a b ...

increases too, which means that the crystalliser is operated at a lower supersaturation. Increasing the hold-up also implicates ...

materials have good mechanical properties, which is especially important in draft-tube baffled stirred crystallisers (see below, ...

Figure 8.4 Draft-tube baffled continuous crystalliser (adapted from Rohani, 1995) for solid-to-solid bioconversions. Figure 8.5 ...

circulation device. The draft-tube baffled and fluidised-bed crystallisers of Figures 8.4 and 8.5, respectively, are especially ...

withdrawn from a quiescent zone of the crystalliser, and dissolved by the supply of either solvent or heat; the resulting soluti ...

optimisation routine, the optimum process conditions and corresponding minimum costs can be found. In the next treatment, mixing ...

is assumed that the bioconversion obeys zero-order kinetics, and that the biocatalyst inactivates according to first-order kinet ...

In case of zero-order bioconversion kinetics and assuming that in the batch reaction crystalliser the maximum attainable product ...

the substrate costs per kg of product $s equal the substrate concentration in the inflow Csi (in kg·m−^3 ) multiplied with the s ...

Figure 8.6a shows that at kd≤4·10^4 h−^1 (or tb≥1.2·10^4 h; see Box 8.1) in a batch system, constant substrate and biocatalyst c ...

of biocatalyst) increases with increasing kd, as the amount of biocatalyst, not being used up as soon as x=100%, decreases. At k ...

Figure 8.7 The substrate, biocatalyst, investment and operating, downstream-processing, and overall costs per kg of product ($s, ...

biocatalyst can be avoided by making the pores sufficiently small, i.e. smaller than the critical cluster size. Selection of the ...

Hustedt, H., Kroner, K.H., Papamichael, N. (1988) Continuous cross-current aqueous two-phase extraction of enzymes from biomass: ...

Scheckermann, C., Schlotterbeck, A., Schmidt, M., Wary, M., Lang, S. (1995) Enzymatic monoacylation of fructose by two procedure ...

CHAPTER NINE SOLID/GAS SYSTEMS, THEORY AND APPLICATIONS SYLVAIN LAMARE, T.MAUGARD AND MARIE D.LEGOY Laboratoire du Génie Proíéiq ...

The potentials of systems where biocatalysts are suspended in mixtures of substrates and water vapour are relatively unexplored ...

it is possible to increase efficiently the half-life of the enzyme by the addition of enzymes that decompose H2O22 (catalase or ...

such technology could be labeled ‘natural’, because of the absence of organic solvents traditionally used in classical liquid sy ...