Multiphase Bioreactor Design

(23) The boundary conditions for the solution of equations (21) and (23) are: (24) (25) The effectiveness factor for internal ma ...

For reversible Michaelis-Menten kinetics the effectiveness factor expression becomes: (32) Figure 4.7 shows the normalised obser ...

Figure 4.7 Normalised robs as a function of the dimensionless surface concentration of the substrate βS with the Thiele modulus ...

Figure 4.8 Effectiveness factor ηint for Michaelis-Menten kinetics as a function of the Thiele modulus Φ with the dimensionless ...

(37) To better understand this equation, we can think of a spherical catalyst particle made of n concentric layers, like an onio ...

Figure 4.9 Effects of v and Φ on the accuracy of the proposed method for the calculation of the internal mass transfer effective ...

(41) where Bi is the Biot number ( The solution of equation (21) with (24) and (41) as boundary conditions gives the dimensionle ...

Batch Reactors Batch reactors are the most commonly used type of reactor when soluble enzymes are used as catalysts. The soluble ...

considerations. For Michaelis-Menten kinetics, the PFR is preferable to the CSTR as the CSTR requires more enzyme to obtain the ...

(43) Ideal reactors Basically there are three types of ideal reactors: (a) the batch stirred tank reactor (BSTR); (b) the plug f ...

This equation can be integrated for a particular kinetic expression. For the Michaelis- Menten kinetics, (49) equation (48) is: ...

Table 4.4 Reactor performance equations for immobilised biocatalysts Reactor performance equation Kinetic form Kinetic equation ...

Figure 4.10 Comparison of CSTR and PFR performance. immobilised biocatalyst, EW, used in those equations are intrinsic values ob ...

For a CSTR, because the component concentrations are constants, the effectiveness factor does not change in the reactor. While f ...

(61) where E is the effective enzyme activity in the reactor at time t and kd is the first-order decay constant. Substituing thi ...

When viable cells are immobilised on the surface of a support, the cells grow on the available surface area A(m^2 l−^1 ), until ...

or; (74) When K 1 and K 2 are both significant, the product mass balance is given by the mixed growth model: (75) REFERENCES Ari ...

CHAPTER FIVE ADVANCES IN THE SELECTION AND DESIGN OF TWO-LIQUID PHASE BIOCATALYTIC REACTORS GARY J.LYE AND JOHN M.WOODLEY The Ad ...

For each class of biocatalytic process the medium in which the conversion occurs is dependent on the properties of the reactants ...

−Dissolved organic phase damage to biocatalyst Downstream Processing +Isolation of reactant from product +Higher product concent ...