Multiphase Bioreactor Design

CHAPTER SIX ENZYMATIC MEMBRANE REACTORS DUARTE MIGUEL F.PRAZERES AND JOAQUIM M.S.CABRAL Centre for Biological and Chemical Engin ...

biocatalytic conversion, product separation and/or concentration and catalyst recovery into a single continuous operation. It is ...

Figure 6.1 Schematic diagram of a generic continuous enzymatic membrane reactor. Possible locations of the enzyme are shown (in ...

The retention capability of a membrane towards a solute (enzyme, substrate or product) can be quantified by a parameter called t ...

Figure 6.2 Retention of soluble enzymes in membrane reactors by confinement through: a) size exclusion, b) size exclusion via en ...

Isoelectric trapping: the enzyme is trapped between two isoelectric membranes with isoelectric point values far apart as to trap ...

k), as a function of the substrate rejection coefficient, σ. The reactor was modelled as a CSTR (see Prazeres, 1995 for further ...

Membranes and Modules The majority of enzymes (10,000–100,000 daltons), whether native or modified, can be retained in a membran ...

plate and frame, tubular, hollow fibres, spiral wound and ultrafiltration cells (Prazeres & Cabral, 1994). While the permeat ...

Direct Contact Membrane Reactors In this type of membrane reactor, the substrates are added to the same compartment of the react ...

Figure 6.7 Schematic diagram of a dead-end membrane reactor (•— enzyme, S—substrate, P—product, —membrane) across the micropores ...

Figure 6.8 Schematic diagram of a dialysis membrane reactor (•— enzyme, S—substrate, P—product, —membrane) Diffusion Membrane Re ...

Figure 6.9 Schematic diagram of a single-pass diffusion membrane reactor (•—enzyme, S—substrate, P— product, —membrane) Figure 6 ...

slight positive pressure may have to be applied in order to keep the interface in the plane of the membrane and prevent the phas ...

Figure 6.12 Schematic diagram of a multiphasic membrane reactor with dual recycle (•—enzyme, S—substrate, P—product, —membrane) ...

ADVANTAGES AND DISADVANTAGES OF MEMBRANE REACTORS Advantages Membrane reactors have several intrinsic advantages that make them ...

when compared to traditional column reactors with enzymes immobilised on beads (Nakajima et al., 1989, 1993). Important advantag ...

Free enzyme molecules in membrane reactors are subjected to shear forces and frictions generated near the membrane walls. There ...

A good control of both concentration polarisation and fouling effects is essential to maintain constant mass fluxes, and hence p ...

weight products. If size differences are significant, it is possible to continuously fractionate the reaction mixture, and obtai ...