Multiphase Bioreactor Design

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Figure 5.1 Classification of two-liquid


phase biocatalytic processes based on


the solubility of both the substrate (S)


and product (P) molecules. The


biocatalyst may be a whole-cell or an


immobilised enzyme and is assumed to


be present in the aqueous phase.


Dashed lines represent mass transfer


processes.


critical level and maximum use is made of the available activity. Reactor designs and
operating conditions to allow us to achieve these criteria will be discussed later.
Multiphasic systems thus allow high overall concentrations of all substrates in the
reactor, regardless of preferential solubility, while concentrations local to the biocatalyst


Advances in the selection and design of two-liquid phase biocatalytic reactors 125
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