Association for the Advancement of Science. No claim to original US
government works. https://www.science.org/about/science-licenses-
journal-article-reuse.
SUPPLEMENTARY MATERIALS
science.org/doi/10.1126/science.abe9582
Materials and Methods
Supplementary Text
Figs. S1 to S22
References ( 37 – 70 )
MDAR Reproducibility Checklist
Data S1 to S3View/request a protocol for this paper fromBio-protocol.Submitted 24 September 2020; resubmitted 28 December 2021
Accepted 22 April 2022
Published online 5 May 2022
10.1126/science.abe9582Weiet al., Science 376 , 968–973 (2022) 27 May 2022 6of6
RESEARCH | RESEARCH ARTICLE