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Th2 type cells. High-intensity workouts of long duration have also been
reported to increase the Th2 response.
When one arm of the immune system is overactive, balance may be re-
stored by using substances that strengthen the underactive arm or weak-
en the overactive arm.
While many agree the Th1/Th2 ratio may be “imbalanced” in autoimmune
conditions, blindly trying to manipulate the balance may be detrimental.
We must understand which side of the scale is down to restore balance.
Table 10: Immune-Modulating Substances
Stimulate Th1 Cell Production Stimulate Th2 Cell Production
Ashwaganda
Astragalus
Beta-glucan mushrooms and
other immune-boosting
mushrooms
Chlorella and other
algae products*
Echinacea
Estrogen
Glutathione
Gram-negative bacteria
(endotoxin)
Licorice root
Melissa officinalis (lemon balm)
Panax ginseng
Polypodium leucotomos
fern extract (Difur)
Selenium
Viruses
Yoga, restorative exercise
Alcohol
Anatabine
Candida
Cortisol excess
Curcumin from turmeric
DHEA
Genistein
Green tea extract
Lycopene
Parasites
Pine bark extract
Pycnogenol
(natural ingredient in apples)
Quercetin
Resveratrol
Soluble fiber
Vigorous exercise
White willow bark
*Algae may contain high amounts of iodine, which may be problematic in Hashimoto’s.