Hashimoto\'s Thyroiditis Lifestyle Interventions for Finding and Treating the Root Cause

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Intestinal Tight Junctions

Figure 7: Intestinal epithelial tight junctions (TJs) act as a physical

barrier. The intestinal TJs tightly regulate intestinal permeability.

The barrier impairment allows bacterial products and dietary anti-
gens to cross the epithelium and enter circulation. This can induce

inflammation and immunological reactions in tissues such as the
intestines, resulting in both intestinal and autoimmune diseases.

Figure adapted from Suzuki T, Hara H. Role of flavonoids in intestinal tight junction regulation.
The Journal of Nutritional Biochemistry. 2011;22:Fig 1. Reprinted with permission from Elsevier.