Science - USA (2018-12-21)
first helix-turn-helix motif of the TAF12 HFD (Fig. 3D). Thus, we propose that TAF4 and TAF12 within lobe B act to promote the b ...
and extended states that we saw in the free TFIID sample (Figs. 1A and 4, A and B), as well as the“engaged”state we previously d ...
it can be reached by TBP as it travels with the mo- bile lobe A, thus helping the upstream DNA out- compete the inhibitory TAND1 ...
balance ( 50 ). Though many activators have been shown to interact with different TAFs, the stron- gest evidence has been shown ...
K. Guptaet al., Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TF ...
RESEARCH ARTICLE SUMMARY ◥ STRUCTURAL BIOLOGY Structures and gating mechanism of human TRPM2 Longfei Wang, Tian-Min Fu†, Yiming ...
RESEARCH ARTICLE ◥ STRUCTURAL BIOLOGY Structures and gating mechanism of human TRPM2 Longfei Wang1,2,Tian-MinFu1,2†,YimingZhou3, ...
interactions between the P loop of NUDT9H in one subunit and MHR1/2 of a neighboring sub- unit (Fig. 2F). Through these interfac ...
of the ADPR-bound form (Fig. 3F). In the homol- ogous NUDT9 crystal structure [Protein Data Bank (PDB) 1QVJ], the hydrolytic pro ...
disengagement of interface III between NUDT9H andMHR1/2intrans.NUDT9Hislikelybifunc- tional: It inhibits MHR movement in the abs ...
organization of the domains and the TM helices are well defined. In contrast to the clockwise rotation between the ADPR-bound st ...
domain rotation in MHR1/2 and local changes in MHR3, as well as disengagement of the in- tersubunit interaction. This effect of ...
J. Duanet al., Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. S ...
RESEARCH ARTICLE SUMMARY ◥ MOLECULAR MAGNETS A linear cobalt(II) complex with maximal orbital angular momentum from a non-Aufbau ...
RESEARCH ARTICLE ◥ MOLECULAR MAGNETS A linear cobalt(II) complex with maximal orbital angular momentum from a non-Aufbau ground ...
basedonligandfieldparameterization predicted that such a barrier could arise from aJ=^9 / 2 ground state, with increasing mixing ...
(accounting also for interelectron repulsion en- ergy). This splitting is small even relative to that of other two-coordinate co ...
originates solely from the atom itself (i.e., that no substantial covalent bonding occurs). The parameterized CD also enables an ...
1 and 3 show waist-restricted hysteresis loops between−0.7 and 0.7 T up to 5 K. A sudden decline in the magnetization as the fie ...
126.7, 126.4, 125.7, 123.4, 122.0, 114.4, 13.1, 2.9, 2.8 ppm. The same method was used to synthesize HC(SiMe 2 OPh) 3 , which ha ...
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