The Scientist November 2019

(Romina) #1

Does Western blotting give you more trouble than expected? Do you feel like your precious samples are being wasted on bad Westerns? Join MilliporeSigma and
find out how you can improve your Western blots! In this webinar, you will learn general guidelines for performing and troubleshooting your Westerns, such as: 



  • choosing different blotting membranes 

  • considering parameters affecting blotting efficiency 

  • optimizing conditions for immunodetection 

  • saving time with SNAP i.d.® 2.0 and Immobilon® GO
    As the inventors of PVDF Immobilon® membranes, MilliporeSigma knows how informative a good Western can be. Bring your research questions to get the most
    out of this session. This webinar is sponsored by MilliporeSigma.


JUN PARK,PhD
Senior Scientist, MilliporeSigma
The life sciences business of Merck KGaA,
Darmstadt, Germany

WEDNESDAY, OCTOBER 16
11:00 AM - 12:30 PM EASTERN TIME

WATCH NOW!
http://www.the-scientist.com/winning-westerns-millsig

WEBINAR SPONSORED BY:

ONDEMAND


Winning Westerns:
Proven Strategies to Optimize Your Western Blots

G-protein coupled receptors (GPCRs), a class of membrane proteins, are involved in critical cellular signaling pathways that have been shown to be
linked to the onset and cause of many diseases. Determining the structure and function of membrane proteins can be challenging partly due to their
hydrophobic properties, which make solubilization difficult. QTY variants, have 46-56 percent of their transmembrane α-helices altered, but are
water-soluble, maintain stable structures, biologically functional and retain proper ligand-binding activity.


In this webinar, sponsored by NanoTemper Technologies, Shuguang Zhang, who created the QTY code technology, will share applications of his
technology and the use of Prometheus to look at difficult to characterize targets such as amyloids and other disease-related molecules. Silvia
Würtenberger of NanoTemper Technologies will share why Prometheus is the new gold standard for protein stability characterization as it tracks
thermal and chemical unfolding as well as aggregation all in a label-free way.


SHUGUANG ZHANG,PhD
MIT Media Lab
Massachusetts Institute of Technology

SILVIA WÜRTENBERGER,PhD
Product Manager, Prometheus
NanoTemper Technologies

TUESDAY, OCTOBER 22
11:00 AM - 12:30 PM EASTERN TIME

WATCH NOW!
http://www.the-scientist.com/qtycode_nanotemper
TOPICS TO BE COVERED:


  • The QTY code technology which systematically replaces
    hydrophobic amino acids in 7 transmembrane alpha-
    helices of GPCRs

  • Applying the QTY code technology to decipher the
    function of membrane proteins

  • Examining protein stability using Prometheus


WEBINAR SPONSORED BY:

ONDEMAND


QTY Code: A Tool for Designing Detergent-Free
Membrane Proteins and Beyond
Free download pdf