Daily Mail - 27.08.2019

Page 30

Indonesia to

move capital

to Borneo

INDONESIA is to move its capi-

tal from sinking, polluted

Jakarta and create a new city

on the island of Borneo.

President Joko Widodo said

the relocation will take a dec-

ade and cost £26.5 billion.

Jakarta, on Java island, has

a population of 10million,

with another 20million in the

surrounding areas. It is prone

to earthquakes and flooding

and is rapidly sinking.

The new capital, a 445,000-

acre site in the East Kaliman-

tan province, has not yet been

named. Mr Widodo said it was

chosen after studies showed

minimal risk of floods, earth-

quakes or volcanic eruptions.

ghan, said: ‘The idea that exer-

cise makes statin side effects

worse might be a misconcep-

tion – what matters is the

intensity of exercise. Moder-

ate exercise cancelled out the

changes in muscle cells caused

by statins.

‘After 20 years of searching,

we finally have an explanation

for statin-associated muscle

pain, along with a possible

solution. If you weren’t con-

vinced to exercise already,

here’s another reason.’

The study, in JACC: Basic to

Translational Science, found

statins compromise proteins

which control the release of

calcium from muscle cells.

This calcium’s release helps

the muscles contract so we

Could exercise beat

statin side ef fects?

By Victoria Allen

Science Correspondent

MODERATE exercise may be the

best way to beat the most common

side effect from taking statins.
Physical activity is thought to stop the
muscle pain which can come with taking
the cholesterol-busting drugs.
Around six million Britons take statins,
which prevent heart attacks and strokes by
lowering ‘bad’ cholesterol and cost only £20
a year per patient. However, up to one in
five give up the pills because of muscle pain,

and doctors believe tens of thousands die

every year through not taking them.

Evidence that around seven in ten profes-

sional athletes cannot tolerate statins due

to muscle pain has added to the belief that

exercise makes the side effect worse.

But scientists funded by the British

Heart Foundation have now found moder-

ate exercise could actually help, after iden-

tifying the cause of sore and weak muscles.

Their study, using rats and muscle biop-

sies from patients taking statins long-

term, found the drugs cause calcium leaks

from muscle cells.

The researchers, at the University of

Leeds and Sweden’s Karolinska Institute,

discovered rats did not suffer the same

leakage after running on a wheel – sug-

gesting moderate exercise can stop muscle

pain in statin takers.

The study’s author, Leeds’ Dr Sarah Cala-

‘What matters

is the intensity’

can move – but irregular leaks

of calcium can trigger signals

which cause muscle cells to

die in patients whose genes

put them at risk.

The resulting muscle pain is

thought to be worse in those

who exercise intensely for long

periods, as they are already

putting a lot of strain on their

muscles. But those who exer-

cise moderately may improve

their endurance, and stop

changes which lead to pain.

After four weeks on statins,

those rats which exercised

showed no signs of changes to

the proteins or signals which

cause cells to die.

The researchers have not yet

shown that calcium leaks lead

to muscle pain in humans, but

say their findings could still

help doctors identify those at

risk of the side effect.

It can prevent agony of muscle pain, study suggests

Compiled by ETAN SMALLMAN

and ADAM JACOT DE BOINOD

DAY

ON THIS

August 27, 2019

FROM THE DAILY MAIL ARCHIVE

AUGUST 27, 1938

‘TAKE up nudism for the good of your

health,’ is the advice of Rev T. Harre, vicar

of Kenley, Surrey, to his parishioners. He

says in the church magazine: ‘I cannot see

anything that is not in keeping with the

conduct of a good Christian in sitting in

some secluded spot with a book, and letting

the sun and air get to the whole body.’

AUGUST 27, 1956

GO HOME, Diana Dors and take Mr Dors

with you! screamed the New York Enquir-

er’s front page. It claimed that the Dorses’

riotous first Hollywood party had ‘left a bad

taste in the mouths of millions of decent

Americans ... Miss Dors is Britain’s busty

answer to Marilyn Monroe. Denis Hamilton

is her lusty husband — and nobody’s answer

to anything.’

HAPPY BIRTHDAY

JEANETTE WINTERSON,

60. The author won the
    Whitbread Award with
    Oranges Are Not The Only
    Fruit. It told the story of her
    brutal adoptive mother,
    who burnt any books she
    brought home. At 16, Win-
    terson left home to live in a
    Mini, telling her mother her female teenage
    lover made her happy. Mrs Winterson replied:
    ‘Why be happy when you could be normal?’
    ROLAND MOURET, 58. The French model-
    turned-fashion designer is best known for
    the origami-folded Galaxy dress — dubbed
    the most famous dress of the past decade
    and worn by Victoria Beckham, Cameron
    Diaz, Scarlett Johansson and Nigella Law-
    son. Asked for the secret of its success, he
    said: ‘I’m not scared of curves.’

BORN ON THIS DAY

C.S. FORESTER (1899-1966). The Cairo-

born English novelist wrote the Horatio

Hornblower series and The African Queen.

A ‘lost’ book by Forester was published in

only 2011. He had asked for publication of

The Pursued to be delayed because he was

worried the racy thriller, featuring an adul-

terous housewife as its heroine, would

detract from his Hornblower books.

MAN RAY (1890-1976). The

American artist, whose real

name was Emmanuel Rad-

nitsky, has been hailed as

‘one of the greatest photog-

raphers ever’. Famed for his

portraits of Hollywood stars

such as Ava Gardner and

artists Pablo Picasso and

Henri Matisse, a print of

Man Ray’s Glass Tears set an auction record

for a single photograph when it sold for

£112,500 in 1993 to Elton John.

ON AUGUST 27...

IN 1965, The Beatles were unimpressed by

their first and only meeting with Elvis

Presley. John Lennon reportedly said it had

been ‘about as exciting as meeting

Engelbert Humperdinck’.

IN 1979, Earl Mountbatten of Burma was

killed by the Provisional IRA.

WORD WIZARDRY

GUESS THE DEFINITION: Matertal (c 1823)

A) wife-like

B) aunt-like

C) of the morning (Answer below)

PHRASE EXPLAINED

Flog a dead horse. To waste energy on a

lost cause. Coined in the 1800s, it refers to a

rider who hits his animal to make it go

faster; but nothing can be done if the horse

is already dead.

QUOTE FOR TODAY

WHAT we call evil is simply ignorance

bumping its head in the dark

Henry Ford,

U.S. industrialist (1863-1947)

JOKE OF THE DAY

HOW does the moon stay up in the sky?

Moonbeams.

Guess the Definition answer: B