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nature research | reporting summary
April 2018Materials & experimental systems
n/a Involved in the study
Unique biological materials
Antibodies
Eukaryotic cell lines
Palaeontology
Animals and other organisms
Human research participantsMethods
n/a Involved in the study
ChIP-seq
Flow cytometry
MRI-based neuroimagingHuman research participants
Policy information about studies involving human research participants
Population characteristics METSIM is a single-site study comprised of 10,197 men randomly selected from the population register of Kuopio, Eastern
Finland, aged 45 to 73 years at initial examination from 2005 to 2010. FINRISK is a series of health examination surveys carried
out by the National Institute for Health and Welfare (formerly National Public Health Institute) of Finland every five years
beginning in 1972. The surveys are based on random population samples from five (six in 2002) geographical regions of Finland.
Participants were selected by 10-year age group, sex, and study area. Survey sample sizes have varied from 7,000 to 13,000
individuals and participation rates from 60% to 90%. The age-range was 25 to 64 years until 1992 and 25 to 74 years since 1997.Recruitment FINRISK - Multi-site national health examination of adults executed every 5 years since 1972 representing a geographically
diverse cross-section of the country. No major exclusions.
METSIM - Single site population cohort representing older (>= 45 at recruitment) adult males in the city of Kuopio in eastern
Finland. Though a population cohort, recruited only older men due to their increased risk for cardiovascular and metabolic
disease.