Extended Data Fig. 3 | Molecular diversity of progenitors in the
hippocampus. a, Heat map showing the expression levels and identities of
genes in the progenitor subclasses. Known gene expression in each type and
GO enrichments are shown to the right. The graph above shows the distribution
of each subclass by gestational week, and the graph below shows the
subclusters of progenitors. Clusters 1–8: 204, 159, 483, 730, 397, 300, 139 and 74
cells. b, Dot plot for known markers of subtypes of progenitors in Fig. 2b. The
size of each dot represents the percentage of cells in each cluster. Grey-to-blue
gradient shows low-to-high gene expression. Progenitors: 204, 159, 483, 730,
397, 300, 139 and 74 cells. c, Dot plot for novel markers of subtypes of
progenitors. The size of each dot represents the percentage of cells in each
cluster. Grey-to-red gradient shows low-to-high gene expression. Progenitors:
204, 159, 483, 730, 397, 300, 139 and 74 cells. d, Abstracted graph shows the
connection on the transcriptome of different subtypes in the developing
human hippocampus. Each dot represents a single cell, and cell colour
represents the cell type. e, Abstracted graph shows the connection on the
transcriptome of all subtypes in the developing human hippocampus. Each dot
represents a single cell, and cell colour represents the cell type. f, Abstracted
graph shows the connection on the transcriptome of different weeks in the
developing human hippocampus. Each dot represents a single cell, and cell
colour represents the week. g, h, Visualization of eight subtypes of progenitors
in the developing human hippocampus using t-SNE (g), and expression of
known markers using the same layout (h). Grey, no expression; red, relative
expression.