Article
Extended Data Fig. 4 | Lipid-prof ile analysis and expression of inf lammatory
markers in the aortic arch. a, Body weights and lipid-profile analysis of
Plxnd1fl/flApoe−/− and Plxnd1iECKOApoe−/− mice after 10 weeks of high-fat diet
feeding (analysed at 16–17 weeks of age); n = 8. Data are mean ± s.e.m.
b, Representative en face preparations of aortic arches immunostained for
VCA M-1 (n = 3) and MCP-1 (n = 5) from Plxnd1fl/flApoe−/− and Plxnd1iECKOApoe−/−
mice with quantification of f luorescence intensity in fold change; 3–5 images
were taken from the inner curvature of aortic arch of each mouse. Data are
mean ± s.e.m. P values were obtained using two-tailed Student’s t-tests using
GraphPad Prism. *P < 0.05.