National Geographic USA – June 2019

(Nora) #1
KEYTRUDA is a prescription medicine used to treat a kind
of lung cancer called NSCLC. KEYTRUDA may be used with
the chemotherapy medicines pemetrexed and a platinum as
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(advanced NSCLC) and is a type called “nonsquamous”
and your tumor does not have an abnormal “EGFR” or
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IMPORTANT SAFETY INFORMATION
KEYTRUDA is a medicine that may treat certain cancers by
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Call or see your doctor right away if you develop any
symptoms of the following problems or these symptoms
get worse:


  • Lung problems (pneumonitis).-Þ«ÌÃv«iÕÌÃ
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  • Intestinal problems (colitis) that can lead to tears or holes
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  • Liver problems (hepatitis). -}Ã>ÃÞ«ÌÃvi«>ÌÌÃ >ÞVÕiÞiÜ}vÞÕÀÃÀÌiÜÌiÃvÞÕÀiÞiÃ]
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  • Hormone gland problems (especially the thyroid,
    pituitary, adrenal glands, and pancreas). -}Ã> ÃÞ«ÌÃÌ>ÌÞÕÀÀi}>Ã>ÀiÌÜÀ}
    «À«iÀÞ>ÞVÕiÀ>«i>ÀÌLi>Ì]Üi}ÌÃÃÀÜi}Ì
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  • Kidney problems, including nephritis and kidney failure.
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  • Skin problems.-}ÃvëÀLiÃ>ÞVÕ`iÀ>Ã]
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  • Problems in other organs.-}Ã>ÃÞ«ÌÃvÌiÃi «ÀLiÃ>ÞVÕiV>}iÃiÞiÃ}ÌÆÃiÛiÀiÀ
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  • Infusion (IV) reactions that can sometimes be severe and
    life-threatening.-}Ã>ÃÞ«ÌÃvvÕÃÀi>VÌÃ >ÞVÕiVÃÀÃ>}]ÃÀÌiÃÃvLÀi>ÌÀ
    Üiiâ}]ÌV}ÀÀ>Ã]yÕÃ}]`ââiÃÃ]viÛiÀ]Àvii}
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KEYTRUDA immunotherapy + chemotherapy (pemetrexed and a


platinum) for advanced nonsquamous, non–small cell lung cancer that


does not have an abnormal EGFR or ALK gene.


Important Safety Information is continued on the next page.

“ TREATMENTS LIKE KEYTRUDA WITH


CHEMOTHERAPY REALLY BREAK THROUGH


BARRIERS WE HAD NOT LONG AGO.”


—DR. GOETZ KLOECKER


KEYTRUDA will not work for everyone. Results may vary.


WHEN TREATED WITH A COMBINATION OF KEYTRUDA AND CHEMOTHERAPY:

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69% of patients taking KEYTRUDA with chemotherapy
were alive compared with 48% taking chemotherapy alone.
MORE PATIENTS LIVED LONGER

48% of patients taking KEYTRUDA with chemotherapy
saw their tumors shrink compared with 19% taking
chemotherapy alone.

MORE PATIENTS SAW THEIR TUMORS SHRINK

The median duration of response to treatment was 11.2 months for patients treated with a combination of
KEYTRUDA and chemotherapy compared with 7.8 months for those on chemotherapy alone.

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