2019-05-01_Discover

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ally Weinrich knew something was terribly wrong. On two separate occasions, she forgot to pick up her grandkids from school, and she kept mixing
old retired nursing professor had to face reality. Her worsening symptoms — the forgetfulness and confusion, up their names. The 70-year-
the organizing activities —or the normal wear and tear of aging. She lived in a matchless setting, on a lake difficulties communicating weren’t just stress and
in South Carolina, nestled in a bucolic wood. She swam daily and kayaked three days a week. But even her purposefully

healthy lifestyle couldn’t protect her from the darkness she feared most: Alzheimer’s disease. presence of amyloid plaques, the sticky In 2015, imaging tests revealed the
proteins associated with Alzheimer’s disease that collect around brain cells and interfere with relaying messages. Weinrich also eventually learned she carried the
ApoE4 gene, which increases the odds of developing Alzheimer’s. The disease was diagnosed after a neuropsychological evaluation. “I felt a total sense of
hopelessness,” recalls Weinrich, who sank into a deep depression. “I wanted to die.”Shortly after, her husband heard a

ALZHEIMER'S
UNDER
AT TACKArmed with big data,
researchers turn to customized lifestyle
changes to fight the disease. BY LINDA MARSA

Diet

EngagementSocial

LeisureActivity

Exercise

MentalActivity

Sleep

PRINT FEEDBACK


Alzheimer’s Annihilation
(“Alzheimer’s Under Attack,”
December 2018)
Of all the subjects that you have
covered, your article on Alzheimer’s is
by the far the most important. Since
I have a long family history of the
disease, I probably would be in its
throes if I hadn’t eliminated the risk
factors as examined in the article.
I can’t do anything about my genetic
predisposition to Alzheimer’s. And that’s
why, at 81, I only just retired from being
a college adjunct and have kept my
mind active and challenged.
William C. Weckerly
Minneola, Fla.

The Clock Is Ticking
(“The State of Science: Policy,”
January/February 2019)
You questioned the impact that the
“right to try” bill would have, since
the FDA already has a program called
“expanded access,” which allows
patients to request experimental drugs.
When a patient is terminally ill, time
is of the essence. Why would anyone
want to place a middle man in the
way of someone seeking a possible
cure? The time delay caused by the
unnecessary step could impact the
effectiveness of the treatment. The
law rightfully places the decision of
treatment between the patient and
the doctor.
Carole Stowell
Atlantic, Va.

MULTIMEDIA FEEDBACK


The Biggest Step Yet
Genetically modified
organisms, or GMOs, can be
a touchy subject. People who
champion the use of genetic
engineering in produce argue
that it can yield crops that
are potentially more resistant
to pests and droughts, and
can boast better nutritional
value. Others counter that
genetic tinkering could
introduce unintended,
harmful consequences to
the environment and humans.
Now that the USDA will begin
requiring food manufacturers
to roll out GMO labeling in
2020, we asked our readers
on Facebook for their
thoughts on the polarizing
subject.

Windy Lee I’m against
GMOs and fully support
labeling. We have a
right to know what
we’re eating.

33%


YES


NO


67%


NONO


Address letters to: DISCOVER
21027 Crossroads Circle, P.O. Box 1612
Waukesha, WI 53187-
Email: [email protected]

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Do you support
GMO labeling
requirements
for food?

Angela Christine Jones I support
labeling only if we are going to
label all breeding methods. If we
did that, people would start to
realize that a breeding technique
does not have anything to do
with the quality or safety of the
end food product. I don’t think
people actually understand what
they (think they) are afraid of.

MAY 2019. DISCOVER 7

INBOX


Feedback
is edited
for space
and clarity.

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