Science - USA (2020-02-07)

MOSQUITO BIOLOGY Mosquito heat seeking is driven by an ancestral cooling receptor Chloe Greppi^1 , Willem J. Laursen^1 , Gonzalo ...

under 2, which is average for a biological pro- cess. Thus,Ir21ais essential for thermosensing by Cooling Cells in the mosquito, ...

deficit. To assess approach behavior, mosqui- toes were activated by five human breaths and presented a human hand, positioned o ...

(fig.S4,HandI)mosquitoes,thispreferencefor warm blood was significantly reduced. Thus, similar to heat seeking, warmth-promoted ...

POLLINATOR DECLINE Climate change contributes to widespread declines among bumble bees across continents Peter Soroye^1 *, Tim N ...

and colonization separately yields a stronger signal ( 9 ). Results were robust to detection- correction method for measuring sp ...

Projections suggest that recent climate change has driven stronger and more widespread bum- ble bee declines than have been repo ...

greatly exceed those of colonization, contributing to pronounced bumble bee species declines across both Europe and North Americ ...

NEUROSCIENCE Microglia mediate forgetting via complement- dependent synaptic elimination Chao Wang1,2, Huimin Yue1,2, Zhechun Hu ...

contained smaller synaptophysin+puncta (fig. S5, C and D) or PSD95+puncta (fig. S5, E and F). Complement cascades are important ...

Wanget al.,Science 367 , 688–694 (2020) 7 February 2020 3of6 Fig. 2. Microglia mediate forgetting through complement system.(Aan ...

known inhibitor of both classical and alternative complement pathways ( 25 ). We injected AAV- hSyn-DIO-CD55-p2A-mCherry (CD55) ...

( 6 ), for 4 weeks. MEM-treatment significantly increased the number of DCX+cells in the DG, indicating enhanced neurogenesis (f ...

continued until the test (Fig. 4E and fig. S9). PLX was administered after training to deplete microglia. GCV treatment in TK+/− ...

PHASE SEPARATION Valence and patterning of aromatic residues determine the phase behavior of prion-like domains Erik W. Martin^1 ...

SEC-SAXS experiments provided a direct measurement of the global dimensions of the A1-LCD (Fig. 1C). Guinier transformation of t ...

in a qualitatively good fit to theR 2 profile. TheR 2 profiles are largely concentration- independent (fig. S5B), suggesting tha ...

To test the predictions from the lattice-based stickers-and-spacers model, we performed in vitro experiments to quantify the tem ...

calculations predictTcfor Aro--to be below the freezing point of water. This explains why Aro-- does not undergo LLPS over all t ...

from different proteins that are known drivers of LLPS. We identified a strong bias toward uniform distribution of aromatic stic ...