Article reSeArcH
Extended Data Fig. 4 | Significant microbial and metabolic
perturbations during taxonomic dysbioses. a, Alpha diversity
(Gini–Simpson) as a function of the dysbiosis score for the sample
(Pearson correlation –0.60; P < 2.2 × 10 −^16 ). n = 1,595 samples from
130 subjects. b, Seven (chosen for space constraints) most differentially
abundant species not shown elsewhere in this manuscript (n = 1,595
samples from 130 subjects; Wald test; see Methods; full results in
Supplementary Table 15). c, Top 10 differentially abundant acylcarnitines
in dysbiosis (n = 546 samples from 106 subjects; Wald test). Carnitine and
acylcarnitines are more abundant in dysbiotic CD, whereas C20:4 carnitine
is significantly depleted (Supplementary Table 16). d, Top 10 differentially
abundant metabolites during dysbiosis not shown elsewhere in this
manuscript (n = 546 samples from 106 subjects; Wald test; full results in
Supplementary Table 16).