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Interaction Similarity Overlap Origins

Neuroimmunology

Control

How do the NS and IS interact?Are the NS and IS structurally

and/or functionally similar?

To what extent do the NS and IS

overlap, or even constitute a

single system?

Do the NS and IS share common

evolutionary origins?

Does the NS control the IS or the

other way around?

Dantzer (2008, 2018); Ordovas-Montanes et al. (2015); Chavan

et al. (2017)

Steinman (2004, 2012); Kioussis

and Pachnis (2009)

Petrovsky (2001); camacho-Arroyo et al. (2009); Ransohoff

(2009); Steinman (2012)

Ottaviani et al. (2007); Kioussisand Pachnis (2009); Kipnis (2016)Pariante (2015); Chavan and

Tracey (2017)

Figure 5.4 Neuroimmunology: A conceptual tree.

This

figure distinguishes

five different questions raised by current scienti

fic literature in

neuroimmunology, and which in general are insuf

ficiently separated.