Chapter 4
Neurons,
h
ormones, and the Brain
COn
C
ept Map
150 Chapter 4 Neurons, Hormones, and the Brain
Neuroscientists study the brain and the rest of the nervous system to gain a better understanding of
consciousness, perception, memory, emotion, stress, and mental disorders.
The Nervous System: A Basic Blueprint
Methods for studying the human brain:
Do something to the brain and observe the consequences:
- Transcranial magnetic stimulation (TMS):
Briefly inactivates a brain area. - Transcranial direct current stimulation (tDCS): Temporarily
stimulates or suppresses cortical activity.
Intervene in behavior and observe the brain:
- Electroencephalogram (EEG): brain-wave recording.
- Positron-emission tomography (PET) scan: method for
analyzing biochemical activity in the brain. - Magnetic resonance imaging (MRI): method for studying body
and brain tissue, using magnetic fields and special radio receivers. - Functional magnetic resonance imaging (fMRI): Fast MRI
method used to study brain activity associated with specific
thoughts and behaviors.
Mapping the Brain
Central Nervous System
(processes, interprets,
stores information;
issues orders to muscles,
glands, organs)
Brain
Spinal Cord
(bridge between
brain and
peripheral nerves)
Nervous System
Peripheral
Nervous System
(transmits information
to and from the CNS)
Somatic
Nervous System
(controls skeletal
muscles)
Autonomic
Nervous System
(regulates glands,
blood vessels,
internal organs)
Parasympathetic
Nervous System
(conserves
energy, maintains
quiet state)
Sympathetic
Nervous System
(mobilizes body
for action, energy
output)
Communication in the
Nervous System
- Neurotransmitters play a critical role in mood,
memory, and psychological well-being. Serotonin,
dopamine, acetylcholine, and norepinephrine travel
particular paths through the brain; GABA and
glutamate are distributed throughout the brain. - Hormones, chemical substances produced primarily
by the endocrine glands, are released into the
bloodstream and affect many organs and cells.
- Melatonin promotes sleep.
- Oxytocin plays a role in attachment and trust.
- Adrenal hormones, such as epinephrine and
norepinephrine, are involved in emotions, memory,
and stress. - Sex hormones are involved in the physical
changes of puberty; estrogens and progesterone are
involved in the menstrual cycle, and testosterone is
involved in sexual arousal.
- Neuromodulators modify the strength of neural
functions. Most endorphins act as neuromodulators;
they reduce pain and promote pleasure.
Chemical Messengers in the Nervous System
- neurons: basic units of the nervous system, composed
of dendrites, a cell body, and an axon. - glial cells: hold neurons in place as well as nourish,
insulate, and protect them. - nerves: bundles of axons and some dendrites in the
peripheral nervous system. - myelin sheath: speeds up the conduction of neural
impulses and prevents adjacent cells from interfering
with one another. - stem cells: give rise to new neurons throughout
adulthood (neurogenesis).
Communication between neurons occurs at synapses,
most of which develop
after birth:
- Action potential
(change in electrical
voltage) produces a
neutral impulse. - Neurotransmitter
molecules are
released into the
synaptic cleft and
bind to receptor
sites on the receiving neuron. - Receiving neuron becomes more likely to fire or less
likely to fire.
Neural impulse
Axon terminal
Synapticcleft
Receptor
site Receivingneuron
Synaptic vesicles (with
neurotransmitter molecules inside)
Neurotransmitter
molecules
(a)(b) (c)