Science_-_6_March_2020

(singke) #1
new products

SCIENCE sciencemag.org/custom-publishing 6 MARCH 2020 • VOL 367 ISSUE 6482 1157

Produced by the Science/AAAS Custom Publishing Office LIFE SCIENCE TECHNOLOGIES


Flow Reactor for Kilogram-Scale Production
The FlowSyn Maxi from Uniqsis is a high-
throughput flow reactor for process chemists
looking to optimize reaction conditions before
scaling-up synthetic production to multiple
kilograms per day. It combines the benefits
of Uniqsis’ proven FlowSyn technology with
high flow rates (up to 100 mL/min) in a compact, benchtop design.
The highly intuitive user interface quickly guides you through the
process for setting up a flow chemistry reaction. Once set up, the
reactor automatically runs the experiment unattended, ensuring
that critical parameters remain within defined limits. Robustly
constructed from epoxy-coated and bead-blasted stainless steel,
it can be specified with stainless steel, Hastelloy, or polytetra-
fluoroethylene (PTFE) flow paths. The unit is fitted with larger-bore
inlet tubing and upgraded inlet/outlet solenoid valves with bigger
fluidic channels to cope with the increased flow rate. The FlowSyn
Maxi is designed to carry out superheated reactions up to +260°C
(1,400 psi) and cooled reactions down to –70°C—making it one of
the most versatile process-scale flow reactors available.
Uniqsis
For info: +44-(0)-845-864-7747
http://www.uniqsis.com/paproductsdetail.aspx?id=flw_maxi

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this
space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not
implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to http://www.sciencemag.org/about/new-products-section for more information.

and offer high purity and low endotoxin levels ideal for in vivo ap-
plications. The antibodies are targeted against key immune system
proteins, including clinically relevant checkpoint proteins such as
PD-1, CTLA-4, and OX40.
Absolute Antibody
For info: 617-377-4057
absoluteantibody.com

Heparanase and Hyaluronidase Activity Kits
AMS Biotechnology supplies Razie assay kits to measure enzyme ac-
tivity of heparanase and hyaluronidase in cell culture supernatants,
human plasma, biological fluids, and tissue samples. Our kits have
been used for research into anti-inflammatory responses, kidney
disease, cancer research, and intervertebral disc degeneration. Hep-
aranase and hyaluronidase enzymes play an important role in the
extracellular matrix. Our kits provide a solution to the performance
and standardization problems found with traditional measurement
techniques used for these types of enzymes. Each assay is available
in two formats: (1) with enzyme as positive control to demonstrate
digestion/activity, and (2) without positive control, for end-users who
have their own enzyme for use as positive control.
AMS Biotechnology
For info: 800-987-0985
http://www.amsbio.com

Antigen and Antibody Conjugation Kits
The Native Antigen Company offers a selection of complementary,
easy-to-use antibody conjugation kits, with a wide range of labels
suitable for use in most applications. On request we can also under-
take custom conjugation of proteins and antibodies. The kits utilize
a novel chemistry to generate highly reproducible antigen and anti-
body conjugates with a range of different labels, including enzymes,
fluorochromes, and biotin. No reconstitution is required, and these
kits can be used to generate liquid stable conjugates, which are fully
scalable from 0.01 mg to gram scale. Incorporation is highly efficient,
helping to ensure lot-to-lot consistency, low backgrounds, and im-
proved assay sensitivity.
The Native Antigen Company
For info: +44-(0)-1865-595230
thenativeantigencompany.com/conjugation-kits

pQA Portable Quadrupole Analyzer
The Hiden pQA portable gas analyzer is a versatile mass spectrom-
eter and offered with a range of interchangeable sampling inlets to
suit a broad application range. Membrane introduction mass spec-
trometry (MIMS) inlets are offered for analysis of dissolved species
in ground water, fermentation cultures, soil samples, and general
applications where analysis of dissolved species in a liquid sample
is required. The system is suited to gas analysis applications, where
sample volume is small, and for environmental applications where
detection of low concentration levels is required. The pQA system
has a mass range of 200 atomic mass units (amu) and sub-ppb
detection levels; extended mass range to 300 amu is optional. The
system is supplied in a Pelican case and can be powered by a 12-V
supply for field use, battery and/or solar powered, or a 220-V supply
for laboratory use.
Hiden Analytical
For info: +44-(0)-1925-445225
http://www.hidenanalytical.com

Knockout Cell Lines
CRISPR-Cas9 knockout cell lines from Abcam provide you with reli-
able, off-the-shelf, single-gene knockouts, so that you can confidently
interrogate the relationship between genotype and phenotype
without spending months establishing your own knockout cell line.
We provide a large and expanding range of knockouts in immortal-
ized mammalian cell lines, such as HeLa and HEK293T. All knockout
cell lines are Sanger sequenced, and many have additional Western
blot data to confirm knockout at the proteomic level. With our large
range of ready-made knockouts in commonly used cell lines, and
our ever-expanding range of new targets and cell lines, obtaining
your knockout cell line of choice is as easy as buying a reagent. Don’t
see the cell line you need in our catalog? Register your interest for
your desired knockout cell line and we will be in touch if it’s in our
pipeline.
Abcam
For info: 888-772-2226
http://www.abcam.com

Recombinant Antibodies for In Vivo Research
Absolute Antibody offers VivopureX recombinant mouse antibod-
ies for in vivo research in mouse models. The collection consists
of popular antibody clones, many originally obtained from rats or
hamsters, which Absolute Antibody has engineered into mouse
anti-mouse recombinant versions to improve research results. The
antibodies are available in discounted bulk sizes ranging from
1 mg to 100 mg. VivopureX antibodies are species-matched chimeric
antibodies, consisting of a clone’s original antigen-binding variable
domain with a mouse-constant domain, which means they do not
induce neutralizing antibodies in mouse models. In addition, the
antibodies feature engineered effector functions, with fragment
crystallizable (Fc) receptor binding tailored to best suit popular ap-
plications such as depletion, agonism, or blocking. All antibodies are
produced recombinantly for ensured batch-to-batch reproducibility
Free download pdf