Science - 31 January 2020

conceived the study and designed the experiments. M.M. and J.B.-G.
performed behavioral experiments. J.B.-G. performed surgeries and
viral manipulations. A.E.M. and S.B.M. designed and produced the HSV
viruses. A.E.M. and J.D.M. performed the experiments with HSV viruses.
M.M. performed quantitative imaging analyses. M.M. and J.B.-G.
performed statistical analyses. M.M., B.W.B., and J.B.-G. wrote the
paper.Competing interests:The authors declare no competing
interests.Data and materials availability:All source data supporting
the conclusions of the study are published in Figshare data repository

(https://figshare.com/s/6dd880046d1d5d3a1100). AAV vectors and

transgenic mouse lines were obtained under material transfer

agreements with Addgene, the University of North Carolina, Jackson

Laboratories and the Rockefeller University.

SUPPLEMENTARY MATERIALS

science.sciencemag.org/content/367/6477/549/suppl/DC1

Materials and Methods

Figs. S1 to S8

Tables S1 to S5

References ( 18 – 25 )

View/request a protocol for this paper fromBio-protocol.

20 September 2019; accepted 19 December 2019

10.1126/science.aaz5751

Matamaleset al.,Science 367 , 549–555 (2020) 31 January 2020 7of7

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