TltE IMMUNE DIET
Oneofthemmtsumlllful
.....................
dimMmld II Cllaric rastric:llDn.
ft,..._•.......,cutln
-lntaklofupto&Oper
c.t. In,..,...,.,...
..... thattmbanputtwaugll
1111,framflultlllsta ....... lt
...... llfespanand t.althspan,
lwnumberof dknH fnle,_,.
athandoflfa.
lbe ...............
lt~---·utfolwy
~10llll'Wltion,which
prlarttlllsnipalrandu'Vlvlll
pdMliptMrgrowthllnd
repraductlan. c:almle-nlstrfded
an1m111W111tu be ....,,nttar,
metaballcallr lalthler •nd
mmt.llrlharparthan"1ale
a.t..tatwllL TiwrllllOtan
•stroneerlmmune....,-.
~alaric
NltlfdlDn iHJdlemelyhllld10
m111nta1n......av.1utth ...
........... lcltwfthaut
going on• permanent starvatlan
diet. lbellaJlstDdndlvabt•
n~Pllthwllrhlde
Clllls aillld mTOR. Whan Clllaries
....... It~°"'
Initiating ... metaballc calCall8
lhattlanllllans,..svmm Into
famlnemade. 'lhepathWllJan
alsobetaggledoffwlthngs
ailled mTOR lnhlbltDrl, the
balMmawn .........
lbe*°tlgatavldenmlat
ltll•nmunebaallarmmes
fram. clnlCll trt.l bf h blOl9Ch
.....,.NITOAlllD,lmlldln
..........an.orns..
111mm..........., ..
gradual dllc:INofcumwnune
~wlthage<-emm
stmy).a..t,.., lwm1111111J181'1
- p-.,bo-cuiiliullld lbldyof.
........,.memTOR"9hlbitaron
.,.._ ..... or&&who
naiwd•dalltjultberant•flu
vaan. 'lhmeglwnth9chg
shawedastnlnger...,...ta
hlnJedlDnandanuptiofthalr
.,.....geneapreu1an. asome
mpedsoflmmunefwlcllan ..clell'lr"""'9 beHar, .... ..,
Mlnnldr, NITORllWI chief
mlldlmlofflcer.1bechg h•
uaflllldaphase•c111m1
trial farraamns that ani stlU
undnr.19tMlnnkk-andother
ra11•rdwsnotlmalwdinlw
---.. lwprindplea.t
mTOR lnhlbilorl an tl'9lt
lmmunwnce•standl.CunlNG CALORIES
Samepeupla..,.llllHlll:ntwlth
....,,,. .. thoughltian't
offidllV NCllll'lllacl ...
mtl-agatngarimmun..._
drug. 'lh ..... otherwapstD
ac:hllMt mTOR lnhlblllan thaugh.
O•ll lntamllla11,.....- .......,s1ataorC11Drtc
iadiildlanthatlsanaughtD
swltdl off mTORfor •ll10ft
wlllleand ltllobtlinbbandls.
nw. .. v.tausreglnw
lndudingh l.1:8-whldl
lmahnls~whewlng
alllltes far 11 ha&n and ani,
mtfngln anl-haurwlndow.
E¥a'I dane once• W8llr, this
llanefr.llvew.rof lluwln1
...................... th.
Immune....,... Earcilels
•Im• PnMn mTOR inhiliitar.
Ewn If. fasting diet llll't
.,..., .............
,.._..htduwnanhlMt
lmmune·baasllng ellacls.
Amm:llng lo lannla llambarg
atllwUlllvmltyof Mllml
lnFloridl, being obele
..,, 1191th9lnTlunesvstam
tD•llmilu~•belng
lmmun.......__.,.11
........ wHh. dedlne In
thefwlcllanofthelmmme
......... cellsandlaw
praducllanof mlbadllSln
........... ,...., .....
ls being ..... Mpoee I
tlslue ...... -..i:s
....................
sap llambelg. -Sctobelftr
Is ....... with poor
vacclne1...-. ... 1n
peoplewhoaniJIUll.•
1belmmuna
systamtm
many
defen~
Including
dendritkcalls
(lop..,., Md.
rangeofwhftw
blood cells
thatlMltout
and gobble up
or lclU InvadersFor now, probably the best way to gauge your
immune age Is to get your blologlcalage tested,
because the two seem to be roughly correlated.
Regardless, you don't need toknowyour
immune ageto take steps to start lowering it.
Andittumsoutthatmanyoftheemerglng
anti-ageing drugs and mategies do theirstuft
at least in part. by arresting or even reversing
immunosenescence.
Onekeyapproachtokeepingourimmune
age down:relates to the fact that as we get older,
some of our immune cells start to misbehave.
This la especially problematlcfor adasa of
immune cells called neutrophila, the most
commontypeofwhite bloodrell 1hesefonn
part of the innate immune system. the body's
first line of defence agajnstinfedion, and are
the bonlerfom=oftheimmunesystem.
patrolling tilelesslythrough the bloodstream
onthelookoutfor lwmful bacteria. When
they deb!ct: an intruder, they squeeze out of the
blood vessel and barrel towards their target,
~ then take It out in one of three waJI: engu]fing
!; it like Pac-Man, spraying it with deadly
G chemicals or suicidally disgorging theJrDNA
e and throwing it around the invader like a net
~ The process bywhichtheytwmel through
i tissues is caD.ed chemotaxis, and it becomes
; increasingly emtic as we age. Older
§ neutmphils can still detect invaders, but
~become much worse at hunting them down,
.. often blunderinghaplwanlly through tissue