The scientist --life inspiring innovation muscle bound

(singke) #1
09.2018 | THE SCIENTIST 11

Contributors


SEPTEMBER 2018

ANTON OTTAVI; ©


MARYANNE RUSSELL; TED ECKELS


During her early rotations as a medical student in 1973,Gillian Butler-Browne met children
with Duchenne muscular dystrophy who were incurable. She was so drawn to the field of muscle
research that Butler-Browne never completed her medical degree, instead going on to do a
traveling PhD that took her from London to the United States, Germany, and ultimately France,
where she had the opportunity to study muscle at the Pasteur Institute. Not many people were
working on muscle, Butler-Browne says: “There was a niche that nobody was filling in France.”
Currently the Director of the Research Center at the Institute of Myology in Paris, Butler-
Browne will be stepping down at the end of the year to go back to research. She’s interested in
aging muscle and its regeneration, and how exercise can help—she walks at least 10 kilometers
a d ay. At the end of a long d ay, Butler-Browne likes to unwind with music and cooking, both
of which she considers intertwined with her science. She was a vocalist when she made the
switch to medicine and for a while played bass guitar in a folk/rock band. Read about
the effect of exercise on aging muscles in her feature article “The Elderly Muscle” on pg. 48.

Born in India, Sandeep Jauhar moved with his family to Southern California at the age of
eight. Questions about the universe, philosophy, and literature piqued his interest. “One thing
I really wasn’t interested in was medicine,” says Jauhar, now a cardiologist. Visits to his grand-
father’s clinic in New Delhi had disillusioned him. Despite his parents’ wishes for him to be
a doctor, Jauhar started his PhD in physics at the University of California, Berkeley, in 1991.
Midway through his graduate studies, a close friend developed lupus. “In the course of try-
ing to help her with her physical illness, I started voraciously reading everything I could about
medicine and about lupus.” Medicine’s many unknowns intrigued Jauhar, who eventually real-
ized he “wanted to become a doctor after all.”
Between getting his PhD and going to medical school, Jauhar completed a fellowship at Time
magazine that heightened his interest in journalism. The connections he formed there guided
him to an internship at the local newspaper while he attended medical school at Washington
University in St. Louis. In the afternoons, he spent time at the St. Louis Post-Dispatch, where
he would write local stories that in turn made him think of bigger stories—such as one about a
leprosy hospital in Louisiana that he pitched to The New York Times. His first week in Manhattan,
where he served as a medical resident at New York Hospital, The Times published his story. He
went on to write “regular dispatches from the hospital” for the outlet, he says, and continues to do
so. Since then, Jauhar has gone on to publish two best-selling memoirs, Intern and Doctored, on
his experiences in the medical field. For Jauhar, who keeps a journal and describes himself as self-
reflective, writing about his time in the hospital was a “natural outcropping of his work.” Read his
essay, adapted from his latest book, Heart: A History, on pg. 66.

Growing up in Chile, Julio Fernandez was captivated by science at an early age. As an
11-year-old, he received his “first diploma” that attested to his doorbell repair skills. By age
15, he was certified in radio and television repair. These early experiences laid the foundation
for his work at Columbia University, where he now not only studies proteins but also builds
some of the instruments needed to explore the molecules. Fernandez says his love of ideas
keeps him going: “The wonder of understanding something new has never left me,” he writes
in an email to The Scientist. He has two dueling and divergent interests. While Fernandez
is “addicted to computer programming,” he is also drawn to the self-sufficiency of people in
the 19th century. With his wife, Fernandez has a ranch nestled in the mountains near Santa
Fe, New Mexico. “When we get here from NYC [New York City], we step back in time.” With
nature (and bears!) keeping them company, they bake fresh bread, plant fruit trees, and so
on. Read his story on pg. 28 about how a giant protein, called titin, is changing the paradigm
of muscle function.
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