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The stability of enzymatic biocatalysts is of primary importance in the biotechnology, food, chemical, and pharmaceutical industries, but screening
for biocatalyst stability has long been a challenge. Native enzymes may not possess the optimal activity required for a specifi c protein-engineering
need, which is why biocatalysts are often modifi ed to withstand di
erent conditions, such as elevated temperatures or the presence of organic
co-solvents. In this webinar, sponsored by NanoTemper Technologies, learn about Prometheus, a platform that runs nanoDSF technology and how
we are using this system to more e ciently screen biocatalyst candidates by characterizing their stability.

Identifying Novel Biocatlyst Candidates via High-

throughput Stability Monitoring

CRISPR-created Animal Models:

The Technical Lowdown

COMINGSOON

COMINGSOON

THURSDAY, SEPTEMBER 20

12:00-1:00 PM, EASTERN TIME

REGISTER NOW!

http://www.the-scientist.com/EnzymeStability

The webinar video will also be available at this link.

TOPICS TO BE COVERED:

• Identifying and isolating biocatalysts with optimal
  properties based on their stability


• Benefits to understanding target molecule stability
  in selection, optimization, and characterization steps


• Analysis of protein stability using nanoDSF

WEBINAR SPONSORED BY:

WOLF-DIETER FESSNER, PhD

Professor

Organic Chemistry

Technische Univeritat

Darmstadt, Germany

Creating reproducible animal models for long-term studies can often be problematic due to the complexity of the genetic modifi cation(s) required.
Suboptimal design strategies compound the challenges by generating undesired genotypic or phenotypic results. CRISPR-Cas9 or zinc-fi nger nuclease
(ZFN)-based technologies can circumvent the challenges of complex genetic alterations due to the precision inherent to these methods. Beyond these
approaches, which result in constitutive changes to the genome, other genome editing methods are available; these include humanization, conditional
knockout, point mutation, and reporter tagging. Horizon Discovery, the sponsor of this webinar, o
ers custom in vivo model generation services. Join us to
learn how to go from concept to F1 in fi ve months.

BEATE KERN, PhD

Product Manager

NanoTemper Technologies

ANDREW BROWN, MS, MBA

Product Manager, In Vivo

Horizon Discovery

THURSDAY, SEPTEMBER 27

2:30–4:00 PM, EASTERN TIME

REGISTER NOW!

http://www.the-scientist.com/CRISPRanimals

The webinar video will also be available at this link.

TOPICS TO BE COVERED:

• A technical overview of custom animal models
  created with CRISPR


• Custom animal models case studies

WEBINAR SPONSORED BY: