8 ★ FT Weekend 21 March/22 March 2020
P E T E R C A M P B E L L —LONDON
Volvo Cars said its Chinese business
had returned to “normal”, offering a
ray of hope to European and US car-
makers that have shuttered operations
in the face of thecoronavirus pan-
demic.
As the Swedish group closed its US plant
and became the final carmaker to cease
production in Europe, chief executive
Hakan Samuelsson said factories and
dealerships in China were operating
close to pre-shutdown levels.
“All factories are back, and there are
very positive signs of normalisation, all
dealerships are open and showrooms
are showing signs of being very close to
normal,” he told the Financial Times.
“Everybody has the feeling they are
through.”
Carmakers have in the past week
announced the closures of every large
European plant and more than 100
facilities across North and South Amer-
ica in a wave of measures to impede the
spread of the virus.
Volvo is the sector’s last big group to
shut European operations. Jaguar Land
Rover announced on Thursday evening
that it would close all its UK plants in the
coming week.
Volvo’s Swedish plants will close until
April 14, with its Belgian site in Ghent
intending to reopen a week earlier.
“We need to plan for normality after
Easter, to give people a light at the end of
the tunnel,” said Mr Samuelsson. “Let’s
hope that will be the case. Continuing to
Christmas would be a disaster.”
Every other manufacturer, from
Volkswagen to Toyota, has announced
European shutdowns over the past
week, while Ford has closed all sites
across North and South America, and
General Motors and Fiat Chrysler have
shuttered plants across the US, Canada
and Mexico. Ford on Thursday drew
down $15.4bn in credit, as well as can-
celling its dividend to preserve cash, fol-
lowing a complete shutdown of its North
American operations.
Volvo is not looking to tap its credit
line but is reducing pay for staff and
working hours for non-factory employ-
ees, Mr Samuelsson said.
Automobiles
Volvo says China plants almost
back to pre-shutdown levels
TA N YA P OW L E Y
TRANSPORT CORRESPONDENT
Ryanair chief executive Michael
O’Leary and the rest of the airline’s
employees are to take a 50 per cent pay
cut, as Europe’s largest low-cost carrier
prepares for a lengthy shutdown in the
region’s air travel.
The outspoken executive said Rya-
nair was working on a best-case scenario
of two o three months in which flightst
would be grounded and revenues would
vanish as the coronavirus outbreak
wreaks havoc on the industry.
However, in an interview with the
Financial Times, he admitted that “hon-
estly none of us have any idea”.
“All that you can draw on is what
appears to be the Chinese experience.
Both for hope and optimism. They seem
to have no new cases now in the last two
days, that’s three months later but after
very draconian lockdown measures,”
he said.
“If we follow the same pattern as the
Chinese, then I think certainly from our
perspective... we’re talking about a
closedown that will last for at least three
months.”
Ryanair’s move comes asrival easyJet
became the latest airline to warn that it
will ground the majority of its aircraft
from Tuesday following similar action
by airlines.
EasyJet said itwould continue to oper-
ate rescue flights to repatriate custom-
ers and expects most of these to be com-
pleted by Monday. After that it will
operate a minimal schedule of essential
services, mainly on UK domestic routes.
The airline industry has been at the
sharp end of the economic disruption
unleashed by the virus, with many
major carriers lobbying their govern-
ments for financial support and a series
of top executives taking pay cuts along-
side their staff.
Willie Walsh,chief executive of BA
owner IAG, this week took a 20 per cent
pay reduction for the remainder of his
contract after delaying his retirement.
Mr O’Leary said he was waiting for
details from the UK and Irish govern-
ments on programmes to help pay
May. Mr O’Leary said at the end of May
the groupwould have to reassess the sit-
uation. He added that he could not rule
out job cuts further down the line.
Ryanair had cash and cash equiva-
lents of more than €4bn as of March 12.
In addition, the grouphad undrawn
credit lines and nearly 300 aircraft that
it owned with a current value of about
$8bn-$10bn, Mr O’Leary said. He did
not expect the airline to have to draw on
the credit lines for the moment.
Earlier this week, the global airline
industry said it would need up to
$200bn in emergency support as the
travel industry continued to bleed cash.
The International Air Transport Associ-
ation, the airlines’ main trade body, said
the majority of carriers faced running
out of money within two months.
But Mr O’Leary warned he EU had tot
be careful over how it offersstate aid,
saying that governments had to be care-
ful not to create “massive distortion”
with bailouts thatwould leave “well-run
airlines at the mercy of nationalised air-
lines at the end of this process”.
Ryanair chief O’Leary and
staff to take 50% pay cut
3 Prolonged shutdown expected 3 EasyJet grounds planes 3 Sector jobs at risk
JAV I E R E S P I N OZ A , N I C F I L D E S ,
H A N N A H M U R P H Y A N D T I M B R A D S H AW
Netflix and YouTube, two of the world’s
largest online video services, are both
taking the unprecedented step of
reducing picture quality in Europe to
ease pressure on broadband networks.
The two internet groups are responding
tocalls by the European Commission
and some European telecoms compa-
nies to prevent internet congestion, as
more people work and take classes at
home during the coronavirus pan-
demic.
YouTube is the world’s most popular
video site with more than 2bn users tun-
ing in every month, while Netflix had
more than 160m viewers worldwide at
the end of last year, including tens of
millions across Europe.
“We are making a commitment to
temporarily default all traffic in the EU
to standard definition,” YouTube said
yesterday.
etflix said that “given the extraordi-N
nary challenges raised y the coronavi-b
rus”, it would temporarily throttle its
data throughput oo, meaningt some
viewers would see degradation in pic-a
ture quality, in he hopes of reducing itst
traffic by a quarter.
The unprecedented demand for
streaming services to curtail their band-
width usage is a sign of how concerned
the authorities are that broadband net-
works will quickly become overloaded,
as millionswork at home and school
children turn to live video streaming.
Last week, Telecom Italia reported a
70 per cent surge in internet traffic over
its landline network as Italy went into
lockdown, saying a “big contribution”
came from online games such as Fort-
nite. Spanish telecoms operators have
warned of a “traffic explosion”. How-
ever, in the UK, BT hasinsisted hat itst
network will be able to cope with the
increased demand.
Defaulting to standard definition,
rather than the high definition that
most viewers with good internet con-
nections have become used to, could cut
the data required to watch a video by
more than half.
“Netflix has decided to begin reducing
bit rates across all our streams in Europe
for 30 days,” the company said. “We
estimate that this will reduce Netflix
traffic on European networks by around
25 per cent while also ensuring a good
quality service for our members.”
YouTube and Netflix cut
picture quality in Europe
Ryanair expects European flights to be grounded until at least June as the coronavirus outbreak wreaks havoc on the airline industry —Chris Ratcliffe/Bloomberg
workers asDowning Street last night
pledged to meet 80 per cent of employee
wages up to £2,500 a month. Ryanair is
already accessing similar schemes that
have been put in place across many con-
tinental European countries.
“ We a r e f a c i n g a s i t u a t i o n
whereby... airlines and airports are
going to have no customers and no reve-
nues for the next two or three months,”
said Mr O’Leary.
What we’re clearly trying to avoid —“
if at all possible because we have to pre-
serve cash — we want to avoid mass lay-
offs but the only way we can avoid mass
lay-offs in our industry... is going to be
payroll support for the next two to four
months.”
The pay cut would be forApril and
YouTube is to
default all traffic in
the EU to standard
definition in order
to ease broadband
network pressure
New netizensEuropeans take crash course
in buying online groceries— ANALYSIS, PAGE 10
Fund managers joltedNorms are fractured
amid acute and growing pressure— MARKETS, PAGE 11
H A N N A H KU C H L E R— NEW YORK
Biotech start-ups are racing to create
faster and more accurate ways to test for
coronavirus s countries including thea
US and UKstruggle o expand produc-t
tion of existing methods fast enough.
Mammoth Biosciences, co-founded
byJennifer Doudna, one of the scientists
who discovered Crispr gene-editing
technology in 2012, is working with the
University of California San Francisco to
validate a test that it developed for Cov-
id-19 in less than two weeks.
The company, which is backed by
Apple chief executive Tim Cook and
Alphabet’s Verily, has only 32 staff and
no product on the market, but chief
executive Trevor Martin s confidenti
the technology is up to the task.
“This is exactly what [Crispr] tech-
nology is meant to help with: rapid
response to infectious diseases,” he said.
Crispr is a DNA editing process that
up until know has been most commonly
used to try totreat rare genetic diseases.
But it can also be used in diagnostics,
where it can be faster and more accu-
rate, with less risk offalse positives.
According to Mammoth, the test it
has developed takes 30 minutes, com-
pared with about two hours for the cur-
rent one used in the US, and does not
need large lab equipment.
Most of the tests currently in use are
based on a process called real time
polymerase chain reaction, which
amplifies the amount of DNA in a sam-
ple and identifies the virus with a fluo-
rescent marker. The Mammoth test
uses Crispr to search for and highlight
the genetic material of the virus and the
testing kit can be shrunk to the size of a
pregnancy test.
“The long-term advantage f Crispr-o
based diagnostics is they are disposable,
easy-to-use, in a very accessible and
very accurate format,” Mr Martin said.
The company has already published
an initial research paper online so that
other scientists can try out or build on
its techniques.
In Boston, Sherlock Biosciences, co-
founded by another Crispr pioneer,
Feng Zhang from the Broad Institute,
has also developed a test for Covid-
using the technology. The 20-person
start-up is working with molecular diag-
nostics company Cepheid to develop a
test that can run on their machines,
which are owned by many labs.
Rahul Dhanda, Sherlock’s chief exec-
utive and a veteran in infectious disease
diagnostics, said a major advantage of
Crispr-based diagnostics is that they are
rapidly programmable, so do not
become less effective as the virus
mutates. A similar technique is being
researched by Darpa, the research arm
of the US Department of Defense, which
Sherlock would ultimately be allowed to
commercialise. The company is also
working on developing a home testing
kit. “[Crispr] is something that is going
to change healthcare in a way that I
didn’t think diagnostics could,” Mr
Dhanda said.
The businesses that are currently try-
ing to rapidly develop diagnostics face a
similar dilemma to drug companies:
their investment may not pay off after
the pandemic dies down. The diagnos-
tics industry also does not have the
same amount of funding as pharmaceu-
tical companies.
Between 2015 and 2019, start-ups
looking for disease treatments raised
more thansix times the private funding
raised by diagnostics start-ups. In 2018
and 2019, the ratio waseight times,
according to research firm CB Insights.
Even the large existing makers of
diagnosticswould not necessarily bene-
fit from the pandemic, said Puneet
Souda, an analyst at SVB Leerink. Ther-
moFisher and Danaher are worth about
$110bn and $86bn respectively, but the
problems the coronavirus will cause for
their operations may end up outweigh-
ing any boost from sales, he said.
He hopes that in the long run, the out-
break will make governments and regu-
lators much more aware of the impor-
tance of diagnostics.
Tara O’Toole, executive vice-presi-
dent of In-Q-Tel, the CIA’s non-profit
venture capital firm, and former under
secretary of state for science and tech-
nology, said it was a “market failure”
that diagnostics were less valued than
therapeutics.
In the short term, she said, the US
would have to focus on increasing the
volume of tests already in use. But in the
longer term, she called for a road map
for the industry.
“We’re in a diagnostic renaissance
from a technological point of view, and
yet we find ourselves without adequate
diagnostics yet again in a big outbreak,”
she said last week at a US government
event to tap scientific expertise.
The businesses focused on Crispr
diagnostics are hoping their tests will be
approved for use this year but ulti-
mately, the technology may be too ear-
ly-stage to be able to help this time.
Mr Martin said itwas “crazy” that in
2020 wedid not have this kind of rapid
molecular testing thatcould be done
anywhere.
“It is important now and in the
future,” he said. “This will not be the
only time we face an infectious disease
outbreak. We need to be prepared next
time something like this happens.”
Under the Hood age 9p
Lex age 16p
Pharmaceuticals. iotechB
Start-ups race to devise faster and more accurate virus tests
Crispr DNA editing can be
employed in diagnostics with
reduced risk of false positives
Yale Tung Chen, an emergency doctor
in Spain, is at home with coronavirus,
tweeting scans of his lungs from an
ultrasound probe connected to his
smartphone. On the fourth day, he saw
the pneumonia in his lungs was
worsening and added another
experimental drug, an antimalarial
that some clinics in China have tried.
As coronavirus can be diagnosed
and tracked using ultrasoundas well
as molecular tests,device maker
Butterfly iQ hasexperienced a surge in
demand. It aims to increase its
production capacity tenfold in the
second half of the year and has
boosted its executive team, including
Laurent Faracci, a senior executive at
Reckitt Benckiser who will take over as
chief in April.
The Connecticut-based start-up
hopes that its affordability — its kit
costs $2,000 comparedwith between
$25,000 and $50,000 for a
conventional machine — and
portability will allow it to help
overloaded healthcare systems
prioritise Covid-19 patients.
John Martin, Butterfly’s chief
medical officer, said the kit could be
used in pop-up screening clinics or in
patients’ homes.Doctors are also
using it to sharedata about how the
disease progresses, uploading
ultrasounds to the website. “This
device is going to change the way
doctors practise medicine,” he said.
Ultrasound tracker
Surge in demand for
device maker’s kit
‘Airlines and airports
are going to have no
customers and revenues
for two or three months’
MARCH 21 2020 Section:Companies Time: 20/3/2020- 18:42 User:cathy.pryor Page Name:CONEWS1, Part,Page,Edition:USA, 8, 1