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(Sean Pound) #1

Extended Data Fig. 1 | Effect of ablation in a simulated network with hyper-
connectivity (that is, Pconn > 0.4; here, Pconn = 0.4 4). Model network responses
aligned to input (arrow, bottom). Raster plots show a subset of neurons from an
example network. PSTHs show averages across all neurons and networks.
Bottom, excitatory neurons within subnetwork. Middle, excitatory neurons
outside subnetwork. Top, inhibitory neurons. Left, network response before
ablation of 10% of the subnetwork neurons; right, response after ablation.

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