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(Sean Pound) #1

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Extended Data Fig. 5 | BAF and CpG DNA decrease acidic organelles.
a–c, Representative f low-cytometry histograms from three independent
experiments of Lysosensor signal following treatment with BAF or CpG
DNA (a), or BAF with or without CpG DNA (b). c, Quantification of Lysosensor


MFI following treatment with PBS alone (no BAF or CpG DNA; n = 8), BAF (n = 6),
CpG DNA (n = 9), or BAF plus CpG DNA (n = 6) (c). Measurements were taken
from distinct samples and graphs show means ± s.e.m. c, One-way ANOVA with
Dunnet’s post-test compared with PBS controls.
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