136
MEMORY, LEARNING, AND THINKING
How a Memory Forms 137Both neurons firing repeatedly at the same time causes a
chemical cascade within the second cell (see p.26), which
makes it more sensitive to the neurotransmitter, and causes extra
receptors to migrate to the edge of the synapse. A signal travels
back to the first cell, telling it to produce more neurotransmitters.Now, a single action potential causes the release of
more neurotransmitters, carrying the message quickly
and efficiently across the synapse, where it is received by
many receptors. This makes it easier for the second neuron
to be activated, sending its electrical signal onward.2 3
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Emotional memories
When something strongly emotional happens, whether that is good or bad,
stress chemicals such as adrenaline and noradrenaline are released. These
make it easier for long-term potentiation to occur with fewer repetitions.
This explains why emotionally arousing memories are stored more rapidly
in the brain and why they are easier to recall than nonemotional memories.1
Hormone released
Noradrenaline released
by neurons originating in the
locus coeruleus triggers a cascade
of changes within cells in
the hippocampus.More
receptors
move to
membrane
surfaceMore receptors
on receiving
cellPhosphates guide
receptors to insert
themselves next to synapseNeurotransmitter
releasedMore neurotransmitters
produced and
releasedRepeated activation causes
more neurotransmitters
to be releasedStrong
connection
allows
signal to
pass quicklyNeurotransmitterPhosphate2
Strong connection
An enzyme adds
phosphate groups to receptors
in the postsynaptic neuron. This
makes it easier for more receptors
to be inserted in the cell membrane,
so the connection is strengthened
and the memory forms easily.Noradrenaline
released by neurons
in locus coeruleus,
located in ponsLOCUS
COERULEUS
PONS
Changes
triggered in
hippocampal
neuronsAction potential
triggered in
second neuronHIPPOCAMPUS
KEY
Neuron is
primed for
connectionAction potential
triggered easilyAction potential in
presynaptic neuron triggers
neurotransmitter releaseUS_136-137_How_memory_forms.indd 137 20/09/2019 12:36