THE BRAIN OF THE FUTURE
The Unexplored Brain 186 187TH
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The brain’s relay station
It is already well known that the
thalamus acts as a relay station
for all incoming sensory
information (except smell), but
more is now being discovered
about how it preprocesses this
information in a complex and
selective manner before it travels
to sensory zones in the cortex.
The thalamus is also central for
the regulation of arousal, and,
with its links to the hippocampus,
it plays an important role in
memory. Deep brain stimulation
(see p.185) of the thalamus has
been used to treat conditions
including tremors.Located in the hypothalamus, the
tiny suprachiasmatic nucleus (SCN)
sets the body’s circadian rhythm—
our 24-hour sleep-wake cycle.
This biological clock drives vital
homeostatic functions, including
body temperature, feeding, and
hormone levels. The SCN also
coordinates the activities of many
organs. Microscopic electrodes or
lasers could one day adjust these
cycles and patterns.THE SCN
SCNHeartLiverStomachOvaryHAVE ALL THE
BRAIN’S PARTS
BEEN DISCOVERED?Not yet. In 2018, improved
microscopes uncovered a small
region at the brain–spinal cord
junction, which was named
the endorestiform
nucleus.
Intralaminar nuclei, involved
in consciousness, alertness,
and feelings of painNuclei of anterior lobe, concerned
with learning and memoryVentral anterior
nucleus, involved in
voluntary movementInternal medullary lamina,
a layer of white matterMedial dorsal nucleus,
involved in memoryLateral geniculate
nucleus involved
in visionMedial geniculate
nucleus involved
in hearingLateral nuclei
(pulvinar), crucial
for visual
cognitionThalamic nuclei
Investigations into lesser-known nuclei are revealing
lots of surprises. For example, the pulvinar nucleus
helps the vision centers map out and measure
a scene and how we reach
out to objects there.DESPITE ITS BODY-WIDE
EFFECTS, THE SCN
CONTAINS ONLY 20,000
NEURONS AND IS
SMALLER THAN
THIS LETTER O
US_186-187_Unexplored_brain.indd 187 20/09/2019 12:38