48
THE PHYSICAL BRAIN
The Adult Brain 49
Disrupting memories
New brain cells help store information, so boosting
neurogenesis in the brain can improve learning into
adulthood. However, it also has a role to play in
forgetting. Adding in new brain cells with new
connections disrupts existing memory circuits
by competing with them. This means there is
an optimal level of neurogenesis, which balances
learning ability with retaining older memories.
New neurons
Neurons grow from stem
cells, dividing, specializing,
and maturing into
functional brain cells.
Memory storage
Due to the creation
of new brain cells,
hippocampal memories
may degrade before
they can be stored in
the cortex. This might
explain why we are
unable to remember
our infancy.
Neurogenesis
Neurogenesis is the development of new neurons by neural stem cells
(cells that can become other cells). In a range of mammals, neurogenesis
happens in the hippocampus and olfactory areas and continues
throughout life, with new neurons being produced regularly.
The same is thought to be true in humans, although the evidence is
mixed. Neurogenesis may also play a role in learning and memory.
TYPE 1
STEM CELL
TYPE 2B
STEM CELL
TYPE 3
STEM CELL
E A R LY
IMMATURE
NEURON
L ATE
IMMATURE
NEURON
MATURE
NEURON
TYPE 2A
STEM CELL
Axons and
dendrites
develop
Mature axons
and dendrites
allow neuron
to integrate
with cell
network
NORMAL
MEMORY PATH
DISRUPTED
MEMORY PATH
HIPPOCAMPUS CORTEX
Memory forms
in hippocampus
New neurons
develop in
hippocampus
Memory
retained
long-term
Memory
poorly
retained
Consolidation
disrupted by new
neurons
Memory
consolidated and
transferred to cortex
W
OR
K
M
OR
AL
ITY
FU
TU
RE
THE VOLUME OF
WHITE MATTER
IN A PERSON’S
BRAIN PEAKS
AROUND
AGE 40
US_048-049_Adult_brain.indd 49 20/09/2019 12:32