FEBRUARY 29 2020 LISTENER 23
Jackson says the
number of people
being treated in the
highest risk group
should be a lot higher
and he is surprised it
is so low. “We need to
be doing a lot better
for them.” He says
although 90% of eli-
gible people have
had a cardiovascular
risk assessment, the
Ministry of Health
doesn’t know the
results because the
data is much harder
to extract in a con-
sistent way nationally
from GP records. It
also doesn’t know if
similar proportions of
people regionally are
receiving the treat-
ment they should be.
“Comparing regions
is a very powerful
tool for improvement
because if some areas
are out of step with
others it’s a good
opportunity to find
out why.”
The work provides
health policymakers
with quite detailed
data on regional dif-
ferences in risk and
treatment practices
- and in effect, at the
click of a button, pro-
vides an individual
predicted heart disease risk assessment for
almost every adult New Zealander and links
it with their current treatment status. It
sounds like Big Brother, but Jackson empha-
sises the only goal is to improve equity in
heart health through accurate risk-assess-
ment tools and quality-improvement
programmes. “Privacy is at
the forefront of our minds
and has been since we started
collecting data in 2002.”
This will become increas-
ingly important as the
researchers hope to expand
the databases they mine
for information, including
mammograms and retinal
photographs (for informa-
tion about vascular health),
CT scans,
body-mass-
index data
from general
practice and
hospital discharge summa-
ries. Should we worry about
a data breach? Jackson says
no – all the data is encrypted
at source, already stripped
of names and addresses.
He says data sovereignty is
paramount, encryption is
military strength and audits are stringent.
He expects that if the additional informa-
tion is sought, it’s likely an independent
watchdog would oversee it.
New research is investigating the best
treatments post-heart attack, too, when
patients are routinely prescribed three drugs
- aspirin to thin the blood, statins to lower
cholesterol and a drug to lower blood pres-
sure. Christchurch Heart Institute senior
clinical lecturer Dr Philip Adamson, an
interventional cardiologist, is investigat-
ing whether blood tests can predict those
patients who have an increased risk of
internal bleeding from the blood-thinning
treatment and those who may be at higher
risk of a further heart attack.
PREDICTING THE FUTURE
About one in five of the 10,000 people
a year admitted to hospital with a heart
attack will die within 12 months, about
half of those from heart-related causes. But
others will die or become ill with bleeding
complications. In a Heart Foundation-
funded study, Adamson will measure levels
in the blood of recently discovered proteins
that may provide information about the
risks of both another attack and serious
bleeding.
His group have already shown
the benefits of measuring levels
of troponin – which increase
when heart muscle is damaged
- when patients are convalescing
after hospital discharge. “When
it is measured, even about four
months after a heart attack, it’s a
very useful marker of future heart
problems. Based on that, we think
there might be an opportunity
when patients are being followed
up by their GP or cardiologist six
to eight weeks after an attack to
make some more personalised
treatment decisions.”
For the first year after their heart
attack, patients are routinely prescribed a
second blood thinner because the combina-
tion with aspirin reduces repeat attacks by
about a quarter to a third. In a second study,
funded by the Health Research Council,
Adamson will investigate whether some
patients would be better off receiving the
two thinners for only three months.
He says doctors tend to adopt a “one size
fits all” approach to heart-attack treatment,
presuming every patient is at increased risk
of a further event. “That’s true, but the risk
varies a lot. Some people are at very high
risk and potentially stand to benefit a lot
from our treatments, but many never go
on to have another attack and don’t stand
to benefit much but still face all the risks
[of the drugs] and we are not very good at
separating them out.” l
ST
EP
HE
N
RO
BI
NS
O
N
About one in five of the
10,000 people a year
admitted to hospital
with a heart attack will
die within 12 months.
Recently discovered
proteins may provide
information about
the risks of another
heart attack and
serious bleeding.
From top,
epidemiologist
Rod Jackson, Heart
Foundation medical
director Gerry Devlin
and interventional
cardiologist Philip
Adamson.