Article
Extended Data Fig. 3 | ipRGCs inf luence the IGL–SCN circuit during early
postnatal stages. a, b, Representative actograms obtained from Opn4a t t n n DTA
mice housed under TRF (a). A score analysis was performed for all actograms
obtained (b). Data are mean ± s.e.m. (n = 6 control mice, 8 Opn4a t t n DTA mice),
Student’s t non-parametric (Mann–Whitney) test, two-tailed. c, Representative
coronal sections obtained from wild-type control and enucleated mice are
shown. NPY+ fibres were measured in the SCN area. Five independent
experiments were performed with similar results. d–g, Representative
actograms obtained from wild-type mice enucleated at P0 (d), P40 (e) or P90
(f) under TRF. A score analysis was performed for all actograms obtained (g).
Data are mean ± SEM (n = 5 control, 6 En P0, 11 En P40 and 8 En P90 mice),
Student’s t non-parametric (Mann–Whitney) test, two-tailed. Scale bar, 100 μm.