Article
Extended Data Fig. 5 | IpRGC input to SCN during early postnatal stages
inf luences afferent IGLNPY projections. a, Npycre/+ mice, with or without
bilateral enucleation at P0, were injected in the IGL with Cre-dependent
A AV-tdT-Syn-GFP. b, Representative IGL injections in adult control and P0
enucleated Npycre/+ mice are shown. Three independent experiments were
performed with similar results. c, d, Axonal projections (tdTomato) (red) from
IGLNPY cells and their synaptic terminals (syn–GFP) (green) are shown (c). IGLNPY
synaptic terminals were quantified (d). Data are mean ± s.e.m. (n = 3 mice for
each condition), two-tailed Student’s t-test. Scale bars, 200 μm (b), 100 μm (c).