Nature - USA (2019-07-18)

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Letter reSeArCH


Extended Data Fig. 8 | Insert size distributions for ATAC-seq
experiments, and track figures demonstrating peak reproducibility
across ATAC-seq replicates. a, Representative insert size distributions
computed from individual ATAC-seq experiments based on aligned
read pairs, showing modes corresponding to nucleosome-free regions,


mono-nucleosomal fragments, and di-nucleosomal fragments. b, Signal
tracks for individual replicate ATAC-seq experiments at the Runx2,
Plekha5 and Mbnl1 loci show reproducibility of accessibility events. DEseq
scaling factors estimated from the atlas of IDR-reproducible peaks were
used for library size normalization.
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