202 10 APRIL 2020 • VOL 368 ISSUE 6486 sciencemag.org/custom-publishing SCIENCE
new products: DNA-RNA analysis
LIFE SCIENCE TECHNOLOGIES Produced by the Science/AAAS Custom Publishing Office
RNA-Seq Library Prep Kit
The SEQuoia Complete
Stranded RNA Library
Prep Kit overcomes
common challenges
often experienced with
traditional RNA-Seq
library preparation kits. Using the kit, scientists can capture the
complete transcriptome, including short [<200 base pairs (bp)]
and long (>200 bp) RNAs, in a single library prep. This innovative
approach is compatible with a broad range of sample inputs from
Illumina sequencers in less than 4 h. The kit includes access to
the integrated SeqSense Analysis Solution and Toolkit software
packages.
Bio-Rad Laboratories
For info: 800-424-6723
http://www.bio-rad.com/sequoia-complete
Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this
space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not
implied. Additional information may be obtained from the manufacturer or supplier.
Electronically submit your new product description or product literature information! Go to http://www.sciencemag.org/about/new-products-section for more information.
Circulating Cell-Free DNA Isolation Kit
AMS Biotechnology has expanded its range of cfPure Cell-Free DNA
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to purify circulating cell-free DNA (cfDNA) from <1 mL to >10 mL
recovery of 100 base pairs (bp)–500 bp DNA fragments in order to
maximize recovery of cfDNA that can be used for a wide range of
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quantitative PCR. The cfPure protocol is quick and easy, allowing
users to process several samples in 1 h or less and making it ideal for
biomarker screening. Designed for scalability, cfPure kits let you use
just the number of beads and amount of reagent you need for your
cfDNA extraction.
AMS Biotechnology
For info: 800-987-0985
http://www.amsbio.com/circulating-cell-free-dna.aspx
Next-Generation Sequencing Panel
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(LOH) as well as somatic variants, even at low allele frequency. It
has been tested to show excellent concordance with array data,
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at 5 megabases (Mb)–10 Mb. This comprehensive panel covers all the
most up-to-date, evidence-based genes and genomic aberrations for
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by replacing multiple assays with a single assay.
Oxford Gene Technology
For info: 914 - 467-5285
w w w.ogt.com/cll
RNA Sequencing and Data Analysis Services
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services. HTPathwaySeq generates in-depth information on
drug mode of action, highlights molecular similarities between
compounds, and reveals potential compound-induced toxicities.
It provides critical data for candidate prioritization for further
drug development. HTTargetSeq supports development of
RNA targeting oligonucleotides, such as short interfering RNAs
and antisense oligonucleotides. HTTargetSeq addresses a key
therapeutic targets. Both HTPathwaySeq and HTTargetSeq are
performed directly on cell lysates from 96-well culture plates. A
typical experiment assesses 94 conditions plus internal controls in
quadruplicate (384 samples). To facilitate data interpretation, results
are shared through Savanna, Biogazelle’s proprietary visualization
app.
Biogazelle
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services.biogazelle.com
Self-Delivering siRNA
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transfect cells without additional reagents, virus, or instruments.
Achieve guaranteed gene silencing in cells that have until now been
beyond the reach of conventional RNA interference methods due to
toxicity from transfection reagents, electroporation, or undesirable
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immunological cells ( Jurkat cells, primary T cells, lymphocytes,
peripheral blood mononuclear cells, macrophages); neuronal cells
(primary neurons, glioma cells, organotypic brain slices); primary
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[brain delivery, dermal (skin) delivery, periodontal model].
Horizon Discovery
For info: 800-235-9880
horizondiscovery.com
Custom Plasmid Construction
Ever design a great study only to have to spend a month or more
better spent writing your next grant or collecting more data?
System Biosciences’ Syn2Clone Custom Construct Service is your
done. With Syn2Clone, you can simply select any of our backbone
synthesize the DNA and insert it into your vector. It’s fast (custom
gene synthesis and subcloning in as little as two weeks), reliable,
System Biosciences
For info: 888-266-5066
systembio.com/services/syn2clone-custom-constructs