Nature - USA (2020-08-20)

(Antfer) #1

432 | Nature | Vol 584 | 20 August 2020


Article


Table 1 | Cohort description with number of COVID-19 deaths by patient characteristics


Characteristic Category Number of individuals
(column %)


Number of COVID-19-related deaths
(% within stratum)

Total 17,278,392 (100.0) 10,926 (0.06)


Age 18–39 5,914,384 (34.2) 54 (0.00)
40–49 2,849,984 (16.5) 140 (0.00)
50–59 3,051,110 (17.7) 522 (0.02)
60–69 2,392,392 (13.8) 1,101 (0.05)
70–79 1,938,842 (11.2) 2,635 (0.14)
80+ 1,131,680 (6.5) 6,474 (0.57)


Sex Female 8,647,989 (50.1) 4,764 (0.06)
Male 8,630,403 (49.9) 6,162 (0.07)


BMI (kg m−2) <18.5 310,721 (1.8) 522 (0.17)
18.5–24.9 4,763,150 (27.6) 3,364 (0.07)
25–29.9 4,682,906 (27.1) 3,068 (0.07)
30–34.9 (obese class I) 2,384,406 (13.8) 1,813 (0.08)
35–39.9 (obese class II) 922,398 (5.3) 762 (0.08)
≥40 (obese class III) 463,042 (2.7) 379 (0.08)
Missing 3,751,769 (21.7) 1,018 (0.03)


Smoking Never 7,924,739 (45.9) 3,598 (0.05)
Former 5,690,966 (32.9) 6,531 (0.11)
Current 2,941,764 (17.0) 708 (0.02)
Missing 720,923 (4.2) 89 (0.01)


Ethnicity White 10,866,411 (62.9) 7,119 (0.07)
Mixed 169,697 (1.0) 62 (0.04)
South Asian 1,022,130 (5.9) 608 (0.06)
Black 339,909 (2.0) 250 (0.07)
Other 320,132 (1.9) 110 (0.03)
Missing 4,560,113 (26.4) 2,777 (0.06)


IMD quintile 1 (least deprived) 3,497,154 (20.2) 1,908 (0.05)
2 3,476,668 (20.1) 2,030 (0.06)
3 3,483,668 (20.2) 2,114 (0.06)
4 3,480,459 (20.1) 2,388 (0.07)
5 (most deprived) 3,340,443 (19.3) 2,486 (0.07)
Blood pressure Normal 3,804,148 (22.0) 2,487 (0.07)


Elevated 2,482,710 (14.4) 1,899 (0.08)
High stage 1 5,548,198 (32.1) 3,281 (0.06)
High stage 2 3,728,241 (21.6) 3,229 (0.09)
Missing 1,715,095 (9.9) 30 (0.00)
High blood pressure or diagnosed hypertension 5,925,492 (34.3) 8,049 (0.14)


Respiratory disease excluding asthma 703,917 (4.1) 2,240 (0.32)
Asthmaa With no recent OCS use 2,454,403 (14.2) 1,211 (0.05)


With recent OCS use 291,670 (1.7) 335 (0.11)
Chronic heart disease 1,167,455 (6.8) 3,811 (0.33)


Diabetesb With HbA1c < 58 mmol mol−1 1,038,082 (6.0) 2,391 (0.23)
With HbA1c ≥ 58 mmol mol−1 486,491 (2.8) 1,254 (0.26)
With no recent HbA1c measure 193,993 (1.1) 444 (0.23)
Cancer (non-haematological) Diagnosed <1 year ago 79,964 (0.5) 220 (0.28)


Diagnosed 1–4.9 years ago 234,186 (1.4) 449 (0.19)
Diagnosed ≥5 years ago 542,320 (3.1) 1,125 (0.21)

Haematological malignancy Diagnosed <1 year ago 8,704 (0.1) 43 (0.49)
Diagnosed 1–4.9 years ago 27,742 (0.2) 120 (0.43)
Diagnosed ≥5 years ago 63,460 (0.4) 173 (0.27)


Continued

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