JUNE 2019
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Theresa Epperly was getting ready for bed after a cook-
out in the summer of 2015 when her throat started to
close up. The 38-year-old’s lips swelled and a rash
sprang up across her skin. At the ER, doctors diagnosed
idiopathic anaphylaxis—medical-speak for “You’re
having a potentially lethal allergic reaction, but we
don’t know why.”
We ek s later, it happ ene d aga i n. Then she ex p er i-
enced a third attack, and blood tests revealed that Ep-
perly had alpha-gal syndrome, an allergy to red meat
caused by a bite from the Lone Star tick. Epperly began
piecing it together: She had pulled off one of the bugs
two years before her first reaction—which happened a
few hours after she’d had steak at the cookout at Lake
Te n k i l le r i n Ok l a hom a.
What’s the link? When a Lone Star tick bites, it
changes the victim’s immune system, resulting in the
development of an allergic sensitivity to alpha-gal—a
sugar found attached to the fats and proteins of animals
the tick feeds on. When the person eats red meat (some-
times years later), their system launches an attack,
causing symptoms that can range from heartburn to a
life-threatening reaction. In some cases, eating dairy or,
in a few very sensitive individuals, consuming products
that contain mammal-derived ingredients like gelatin
may cause issues, says allergist Onyinye Iweala, MD,
Ph D, of t he Un iver sit y of Nor t h C a rol i na at C hap el Hi l l.
As Lone Star ticks spread from the southeast to the
rest of the U.S., red-meat allergy is becoming more
common. One in five people living in hot spots now
show signs of it, according to a study in the Journal of
Allergy and Clinical Immunology, and it’s the leading
reason for anaphylaxis in one Tennessee clinic, besting
peanuts and beestings.
By Carrie Arnold
HEALTH FLASH: LYME DISEASE ISN’T THE ONLY THREAT
FROM THE TINY BUGS. A POTENTIALLY DEADLY ALLERGY
HAS ALSO BEEN LINKED TO THE BLOOD-SUCKING
CRITTERS. HERE’S WHAT YOU NEED TO KNOW.
Ticked Off
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WOMEN’S HEALTH / 7 7