84 ❯ STEP 4. Review the Knowledge You Need to Score High
nucleus, which directs synthesis of such substances as neurotransmitters. The dendrites are
branching tubular processes capable of receiving information. The axon emerges from the
cyton as a single conducting fiber (longer than a dendrite) which branches and ends in tips
called terminal buttons, axon terminals, or synaptic knobs. The axon is usually covered
by an insulating myelin sheath (formed by glial cells). Neurogenesis, the growth of new
neurons, takes place throughout life.
Neurotransmitters are chemicals stored in structures of the terminal buttons called
synaptic vesicles. Different neurotransmitters have different chemical structures and per-
form different functions. For example, acetylcholine (ACh) causes contraction of skeletal
muscles, helps regulate heart muscles, is involved in memory, and also transmits messages
between the brain and spinal cord. Lack of ACh is associated with Alzheimer’s disease.
Dopamine stimulates the hypothalamus to synthesize hormones and affects alertness and
movement. Lack of dopamine is associated with Parkinson’s disease; too much dopamine
is associated with schizophrenia. Glutamate is a major excitatory neurotransmitter involved
in information processing throughout the cortex and especially memory formation in
the hippocampus. Both schizophrenia and Alzheimer’s may involve glutamate receptors.
Node of
Ranvier
Myelin sheath
Nucleus Axon
Cyton or cell body
or soma
Motor or Efferent Neuron
Sensory or Afferent Neuron
Axon terminal
or
Terminal button
or
Synaptic knob
Synaptic gap
Dendrite
terminal button
Nucleus Cell body
Terminal
button
Dendrite
Dendrite
Receptor site
Neurotransmitter
Synaptic vesicle with
neurotransmitters
Enlargement of
terminal button of
presynaptic neuron
and membrane of
dendrite of postsynaptic
neuron at synapse
Figure 7.3 Typical neurons.