CK12 Life Science

(Marvins-Underground-K-12) #1

Figure 5.16: DNA replication occurs by the DNA strands “unzipping”, and the original
strands of DNA serve as a template for new nucleotides to join and form a new strand. ( 21 )


Protein Synthesis


The code of DNA, stored in the base sequences, contains the instructions for the order of
assembly of amino acids to make proteins. Each strand of DNA has many, many separate
sequences that code for the production of a specific protein. These discrete units of DNA
that contain code for the creation of one protein are calledgenes.Proteins are made up of
units calledamino acids, and the sequence of bases in DNA codes for the specific sequence
of amino acids in a protein.


There are about 22,000 genes in every human cell. Does every human cell have the same
genes? Yes. Does every human cell use the same genes to make the same proteins? No. In
a multicellular organism, such as us, cells have specific functions because they have different
proteins, and they have different proteins because different genes are expressed in different
cell types. Think ofgene expressionas if all your genes usually are ”turned off.” Each cell
type only ”turns on” (or expresses) the genes that have the code for the proteins it needs to
use. So different cell types ”turn on” different genes, allowing different proteins to be made,
giving different cell types different functions.


However, DNA does not directly coordinate the production of proteins. Remember that
DNA is found in the nucleus of the cell, but proteins are made on the ribosomes in the
cytoplasm. How do the instructions in the DNA get out to the cytoplasm so that proteins

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