Nature - USA (2020-10-15)

(Antfer) #1

Article


Extended Data Fig. 8 | Comparison of inner gates in TASK2 and other K+
channels. a–g, Stereo views from the membrane plane, highlighting inner gate
regions of selected K+ channels: open MthK (a), closed KcsA (b), open TASK2 (c),
closed TASK2 (d), and closed TASK1 (e). f, An overlay of the TASK2 open and


closed structures with the canonical “bundle crossing” inner gating channels
KcsA and MthK, coloured as in a–d. g, An overlay of the TASK2 open and closed
structures with TASK1, with a distinct inner “X” gate, coloured as in c–e.
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