0100200300400600012461810 214 61820MF1
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MF80100200300400600012461810 214 61820MF9
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MF130100200300400600012461810 214 61820MF14
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MF170100200300400600012461810 214 61820MF23
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MF260100200300400600012461810 214 61820MF 18
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MF 2201002003004006000246Lo D5 Hi D1 + AZTHCTRL Hi D1 Lo D1MF 34
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MF 37PK HiPK LoPK Hi + AZTHDays post infectionDays post infectionDays post treatmentIU / mLabcd e fIU / mLExtended Data Fig. 7 | Plasma ALT levels of cynomolgus macaques treated
with HCQ. In addition to the six SARS-CoV-2-infected groups, three groups of
two macaques were treated but not infected to follow HCQ pharmacokinetics.
a–f, ALT levels in the plasma are shown for all infected macaques (a–e) and the
uninfected, HCQ-treated macaques (f). Shaded zones indicate treatment
periods.