Fundamentals of Anatomy and Physiology

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Cell Structure 53


the nucleus, called nucleoplasm, whereas the outer
nuclear membrane connects with the endoplasmic

reticulum.^



  1. The nuclear membrane is perforated with pores that
    allow materials like messenger RNA to leave the


nucleus and go into the cytoplasm of the cell.^



  1. The genetic material inside the nucleoplasm is darkly
    stained threads of nucleic acids called chro-matin.
    This chromatin will duplicate, shorten, and thicken
    during cell division and will become visible as


chromosomes.^



  1. The nucleolus is a spherical particle within the nu-
    cleoplasm that does not have a covering membrane. It
    is the site where ribosomes are made.


The Mitochondria.


  1. The mitochondria are the powerhouses of the cell.
    Each mitochondrion is composed of two mem-
    branes. The outer membrane forms its capsular
    shape, and the inner membrane folds on itself to


increase surface area.^



  1. The inner folds of the mitochondrion are called
    cristae. It is in the mitochondrion where the aerobic


phase of cellular respiration occurs:^
C 6 H 12 O 6 1 6O 2 S ATP (energy) 1 6CO 2 1 6H 2 O



  1. Cells with higher energy requirements, like muscle
    cells, will have mitochondria with many cristae;
    those with lower energy requirements will have
    fewer cristae.


Lysosomes



  1. Lysosomes are small structures in the cytoplasm
    surrounded by a membrane and contain powerful


digestive enzymes.^



  1. Lysosomes function in three different ways in the
    cell: they function with food vacuoles to digest stored
    food; they function in the maintenance and repair of
    cellular organelles; and they act as suicide agents in
    old and weakened cells.


Endoplasmic Reticulum



  1. The endoplasmic reticulum or ER is a complex
    system of membranes that makes up a collection of
    membrane-bound cavities or channels. These


channels- are called cisternae.^



  1. The ER connects with the outer nuclear membrane
    and with the cell membrane.
    3. There are two types of ER. All cells have a rough or
    granular ER whose membranes have attached
    ribosomes-. The function of a rough ER is pro-tein
    synthesis. Some cells also have a smooth or agranular
    ER, which does not have attached ri-bosomes. The
    function of a smooth ER can be the transportation of
    fats or the synthesis of the sex hormones.


The Golgi Apparatus


  1. The Golgi body or apparatus is a collection of flat
    sac-like cisternae that look like a stack of pancakes.^

  2. They function as points within the cytoplasm
    where compounds to be secreted by the cell are
    concentrated and collected. They act like storage
    warehouses- of the cell.^

  3. If the cell is synthesizing carbohydrates and pro-
    teins, the carbohydrates will be synthesized in the
    Golgi apparatus.


Ribosomes


  1. Ribosomes are small granules distributed through-out
    the cytoplasm and attached to the rough ER. They are
    not covered by a membrane.^

  2. Ribosomes are the site of protein synthesis.


Protein Synthesis


  1. Proteins function in major and essential ways for
    cellular function and survival. They are part of the
    structure of membranes; they act as enzymes or
    catalysts that make chemical reactions occur in the
    cell; and they function in our immune response.^

  2. The code to make a particular protein is a gene on a
    DNA molecule. The DNA is found in the nucleus,
    whereas the protein is made at a ribosomal site in the
    cytoplasm.^

  3. A special molecule called messenger RNA copies the
    code from the DNA molecule in a process called
    transcription. The mRNA then leaves the nucleus
    through a nuclear pore and takes the code to a ribo-
    some or group of ribosomes.^

  4. Other molecules called transfer RNAs go into the
    cytoplasm and pick up particular amino acids. Each
    tRNA molecule is coded for a particular amino acid by
    its anticodon loop at the end of the molecule. The
    anticodon loop will only match a particular site on the
    mRNA molecule called the codon. This pro-cess is
    called translation.

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