BNF for Children (BNFC) 2018-2019
fatigue.increased risk of infection.insomnia.irritability. nausea.vertigo.vomiting ▶UncommonAggression.psychotic disorder lPREGN ...
CARBAGEN®SR Trigeminal neuralgia ▶BY MOUTH ▶Child 5–11 years:Initially 5 mg/kg daily in 1 – 2 divided doses, then increased in s ...
lMONITORING REQUIREMENTS ▶Plasma concentration for optimum response 4 – 12 mg/litre ( 20 – 50 micromol/litre) measured after 1 – ...
lMEDICINAL FORMS There can be variation in the licensing of different medicines containing the same drug. Oral solution CAUTIONA ...
Gabapentin 19-Jul-2017 lINDICATIONS AND DOSE Adjunctive treatment of focal seizures with or without secondary generalisation ▶BY ...
Gabapentin 300 mgNeurontin 300 mg capsules| 100 capsuleP £ 42. 40 DT = £ 8. 09 Gabapentin 400 mgNeurontin 400 mg capsules| 100 c ...
Lamotrigine lINDICATIONS AND DOSE Monotherapy of focal seizures|Monotherapy of primary and secondary generalised tonic-clonic se ...
lRENAL IMPAIRMENTCaution in renal failure; metabolite may accumulate. Dose adjustmentsConsider reducing maintenance dose in sign ...
lPREGNANCY MonitoringThe dose should be monitored carefully during pregnancy and after birth, and adjustments made on a clinical ...
lHEPATIC IMPAIRMENTCaution in severe impairment—no information available. lRENAL IMPAIRMENT Dose adjustmentsHalve initial dose i ...
▶INITIALLY BY SLOW INTRAVENOUS INJECTION ▶Neonate:Loading dose 18 mg/kg, dose to be administered over 20 – 30 minutes, then (by ...
▶Trough plasma concentration for optimum response: neonate– 3 months, 6 – 15 mg/litre ( 25 – 60 micromol/litre); child 3 months– ...
Patients may need to be maintained on a specific manufacturer’s branded or generic rufinamide product. lPATIENT AND CARER ADVICE ...
treatments are ineffective or not tolerated, as judged by an experienced specialist. Use of valproate in pregnancy is contra-ind ...
EPISENTA®CAPSULESContents of capsule may be mixed with cold soft food or drink and swallowed immediately without chewing. EPILIM ...
lSIDE-EFFECTS ▶Common or very commonAggression.agitation.appetite decreased.drowsiness.irritability.movement disorders. muscle t ...
Topiramate 25-Jan-2018 lINDICATIONS AND DOSE Monotherapy of generalised tonic-clonic seizures or focal seizures with or without ...
lMEDICINAL FORMS There can be variation in the licensing of different medicines containing the same drug. Forms available from s ...
thrombocytopenia.urine abnormalities.vasculitis. vomiting.weight increased SIDE-EFFECTS, FURTHER INFORMATION Hepatic dysfunction ...
lUNLICENSED USEGranules not licensed for rectal use. Tablets not licensed to be crushed and dispersed in liquid. Vigabatrin dose ...
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