BNF for Children (BNFC) 2018-2019

lINTERACTIONS→Appendix 1 : antimalarials lEXCEPTIONS TO LEGAL CATEGORYCan be sold to the public provided it is licensed and labe ...

Adjunct in the treatment of non-falciparum malaria caused byP.ovaleinfection ▶BY MOUTH ▶Child 6 months–17 years: 250 micrograms/ ...

Falciparum malaria ▶BY MOUTH ▶Child: 10 mg/kg every 8 hours (max. per dose 600 mg) for 7 days, to be given together with or foll ...

Quinine sulfate 300 mgQuinine sulfate 300 mg tablets| 28 tabletP£ 2. 83 DT = £ 1. 96 5.3 Toxoplasmosis ANTIBACTERIALS›MACROLIDES ...

6.2 Hepatitis infections 6.2aChronic hepatitis B Other drugs used for Chronic hepatitis BInterferon alfa, p. 557 .Lamivudine, p. ...

psychiatric condition.severe debilitating medical conditions.severe, uncontrolled cardiac disease in children with chronic hepat ...

DOSE ADJUSTMENTS DUE TO INTERACTIONS ▶Manufacturer advises reduce dose of concurrent H 2 - receptor antagonist if above a dose c ...

lINTERACTIONS→Appendix 1 : interferons lSIDE-EFFECTS ▶Common or very commonAlopecia.anaemia.anxiety. appetite decreased.arthralg ...

require prophylaxis with varicella-zoster immunoglobulin (see under Disease-specific Immunoglobulins). Prophylactic intravenous ...

▶BY INTRAVENOUS INFUSION ▶Neonate: 10 – 20 mg/kg every 8 hours for at least 7 days. ▶Child 1–2 months: 10 – 20 mg/kg every 8 hou ...

Aciclovir 800 mgAciclovir 800 mg dispersible tablets| 35 tabletP£ 65. 00 DT = £ 10. 98 ▶Zovirax(GlaxoSmithKline UK Ltd) Aciclovi ...

Reduce dose according to estimated glomerular filtration rate forcytomegalovirus prophylaxisfollowing solid organ transplantatio ...

Valganciclovir 31-May-2018 lINDICATIONS AND DOSE Prevention of cytomegalovirus disease [following solid organ transplantation fr ...

lRENAL IMPAIRMENT Dose adjustmentsReduce dose; consult product literature. lMONITORING REQUIREMENTS ▶Monitor electrolytes, parti ...

The protease inhibitors include atazanavir p. 423 , darunavir p. 423 , fosamprenavir p. 425 (a pro-drug of amprenavir), lopinavi ...

ANTIVIRALS›HIV-INTEGRASE INHIBITORS Dolutegravir 05-Jun-2018 lDRUG ACTIONDolutegravir is an inhibitor of HIV integrase. lINDICAT ...

▶Neonate up to 7 days (body-weight 4 kg): 7 mg once daily. ▶Neonate 7 days to 28 days (body-weight 2 kg): 8 mg twice daily. ▶Neo ...

ANTIVIRALS›NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS Efavirenz lINDICATIONS AND DOSE HIV infection in combination with oth ...

lINTERACTIONS→Appendix 1 : etravirine lSIDE-EFFECTS ▶Common or very commonDiabetes mellitus.diarrhoea. headache.hyperglycaemia.m ...

OsteonecrosisOsteonecrosis has been reported in patients with advanced HIV disease or following long-term exposure to combinatio ...