BNF for Children (BNFC) 2018-2019

lactate 25 mmol/litre;Volplex®contains succinylated gelatin (modifiedfluid gelatin, average molecular weight 30 000) 40 g( 4 %), ...

▶Child 12–17 years:Initially 4 – 8 mmol 3 times a day, dose to be adjusted as necessary, dose expressed as Mg (^2) + DOSE EQUIVA ...

lDIRECTIONS FOR ADMINISTRATION ▶With intravenous useIn severe hypomagnesaemia administer initially via controlled infusion devic ...

lMEDICINAL FORMS There can be variation in the licensing of different medicines containing the same drug. Capsule ▶Alu-Cap(Meda ...

2.4bHypophosphataemia ELECTROLYTES AND MINERALS›PHOSPHATES Phosphate lINDICATIONS AND DOSE Hypophosphataemia|Hypophosphataemic r ...

lCONTRA-INDICATIONSHyperparathyroidism.metastatic carcinoma.multiple myeloma.obstructive bowel disease. reduced gut motility (in ...

▶Child: 1 – 2 mmol/kg daily, dose dependent on deficit or the daily maintenance requirements Potassium depletion ▶BY MOUTH ▶Neon ...

Urea cycle disorders Sodium benzoate p. 614 and sodium phenylbutyrate p. 615 are used in the management of urea cycle disorders. ...

.Mefenamic acid (safety uncertain, contact UKPMIS for advice) .Meprobamate .Methyldopa .Metolazone .Metyrapone .Mifepristone .Mi ...

solution ( 30 %) not licensed in children over 12 years. Not licensed for use in organic acidaemias. lCAUTIONSDiabetes mellitus ...

lPRESCRIBING AND DISPENSING INFORMATION Mercaptamine has a very unpleasant taste and smell, which can affect compliance. lHANDLI ...

0. 2 micronfilter at an initial rate of no more than 15 mg/hour; for subsequent infusions, infusion rate may be increased gradua ...

Velaglucerase alfa lDRUG ACTIONVelaglucerase alfa is an enzyme produced by recombinant DNA technology that is administered as en ...

occur, manufacturer advises immediate discontinuation of treatment and initiation of appropriate medical treatment. For informat ...

3.9 Mucopolysaccharidosis ENZYMES Elosulfase alfa 04-Dec-2017 lDRUG ACTIONElosulfase alfa is an enzyme produced by recombinant D ...

lCAUTIONSAcute febrile respiratory illness (consider delaying treatment).infusion-related reactions can occur. severe respirator ...

Dose adjustmentsChild 12 – 17 years, initially 200 mg twice daily if estimated glomerularfiltration rate 50 – 70 mL/minute/ 1. 7 ...

Nitisinone 10 mgOrfadin 10 mg capsules| 60 capsuleP £ 2 , 062. 00 Nitisinone 20 mgOrfadin 20 mg capsules| 60 capsuleP £ 4 , 512. ...

according to plasma-ammonia concentration, the total daily dose may alternatively be given in 3 – 4 divided doses IMPORTANT SAFE ...

DRUGS FOR METABOLIC DISORDERS› AMMONIA LOWERING DRUGS Glycerol phenylbutyrate 14-May-2018 lDRUG ACTIONGlycerol phenylbutyrate is ...