BNF for Children (BNFC) 2018-2019

lPREGNANCYDoes not cross the placenta; maternal osteoporosis reported after prolonged use; multidose vials may contain benzyl al ...

Innohep 16 , 000 units/ 0. 8 ml solution for injection pre-filled syringes| 6 pre-filled disposable injectionP£ 57. 12 | 10 pre- ...

Treatment and prophylaxis of thrombotic episodes following induction dose (if INR above 3. 5 ) ▶BY MOUTH ▶Neonate (under expert ...

Astatincan be of benefit in older children who have a high risk of cardiovascular disease and have hypercholesterolaemia. Hypert ...

hypertension. It is used either alone or as an adjunct to other drugs. Sildenafil is a selective phosphodiesterase type- 5 inhib ...

ACE inhibitors are therefore best avoided in those with known or suspected renovascular disease, unless the blood pressure canno ...

ANTIHYPERTENSIVES, CENTRALLY ACTING Clonidine hydrochloride 01-Jun-2017 lINDICATIONS AND DOSE Severe hypertension ▶BY MOUTH ▶Chi ...

used intravenously for the treatment of hypertension particularly in the peri-operative period. Beta-blockers can be used to con ...

BETA-ADRENOCEPTOR BLOCKERS› ALPHA- AND BETA-ADRENOCEPTOR BLOCKERS eiiiiF 103 Labetalol hydrochloride lINDICATIONS AND DOSE Hyper ...

Thyrotoxicosis (adjunct) ▶BY MOUTH ▶Neonate:Initially 250 – 500 micrograms/kg every 6 – 8 hours, adjusted according to response. ...

▶Beta-Prograne(Tillomed Laboratories Ltd, Actavis UK Ltd, Teva UK Ltd) Propranolol hydrochloride 160 mgBeta-Prograne 160 mg modi ...

lBREAST FEEDINGManufacturer advises avoidance. lRENAL IMPAIRMENTManufacturer advises caution. lDIRECTIONS FOR ADMINISTRATIONGive ...

Calcium-channel blockers f lDRUG ACTIONCalcium-channel blockers (less correctly called‘calcium-antagonists’) interfere with the ...

lCAUTIONSCongestive heart failure.elevated intracranial pressure.increased risk of serious hypotension.portal hypertension.pulmo ...

lMEDICINAL FORMS There can be variation in the licensing of different medicines containing the same drug. Forms available from s ...

lRENAL IMPAIRMENTThiazides and related diuretics should be used with caution because they can further reduce renal function. The ...

dry mouth.dyspnoea.electrolyte imbalance. gastrointestinal discomfort.headache.hypotension. myalgia.nausea.palpitations.paraesth ...

4 mg/kg daily in divided doses, ongoing doses should only be given if test dose tolerated ▶Child 1–11 years:Test dose 100 microg ...

carefully for 1 – 2 hours, maintenance 10 – 20 mg daily in 1 – 2 divided doses; maximum 40 mg per day Diabetic nephropathy (unde ...

Lisinopril 5 mgLisinopril 5 mg tablets| 28 tabletP£ 7. 80 DT = £ 0. 46 Lisinopril 10 mgLisinopril 10 mg tablets| 28 tabletP£ 11. ...