BNF for Children (BNFC) 2018-2019

(singke) #1
▶Child 12–17 years: 200 – 400 micrograms once daily (max.
per dose 800 micrograms), dose to be given in the
evening
Prophylaxis of asthma
▶BY INHALATION OF POWDER
▶Child 6–11 years: 100 – 400 micrograms twice daily, dose
to be adjusted as necessary
▶Child 12–17 years: 100 – 800 micrograms twice daily, dose
to be adjusted as necessary
▶BY INHALATION OF NEBULISED SUSPENSION
▶Child 6 months–11 years: 125 – 500 micrograms twice
daily, adjusted according to response; maximum 2 mg
per day
▶Child 12–17 years:Initially 0. 25 – 1 mg twice daily,
adjusted according to response, doses higher than
recommended max. may be used in severe disease;
maximum 2 mg per day
BUDELIN NOVOLIZER®
Prophylaxis of asthma
▶BY INHALATION OF POWDER
▶Child 6–11 years: 200 – 400 micrograms twice daily, dose
is adjusted as necessary
▶Child 12–17 years: 200 – 800 micrograms twice daily, dose
is adjusted as necessary
Alternative in mild to moderate asthma, for patients
previously stabilised on a twice daily dose
▶BY INHALATION OF POWDER
▶Child 6–11 years: 200 – 400 micrograms once daily, to be
taken in the evening
▶Child 12–17 years: 200 – 400 micrograms once daily (max.
per dose 800 micrograms), to be taken in the evening
PULMICORT®RESPULES
Prophylaxis of asthma
▶BY INHALATION OF NEBULISED SUSPENSION
▶Child 3 months–11 years:Initially 0. 5 – 1 mg twice daily,
reduced to 250 – 500 micrograms twice daily
▶Child 12–17 years:Initially 1 – 2 mg twice daily, reduced
to 0. 5 – 1 mg twice daily
Croup
▶BY INHALATION OF NEBULISED SUSPENSION
▶Child: 2 mg for 1 dose, alternatively 1 mg for 2 doses
separated by a 30 minute interval, dose may be
repeated every 12 hours until clinical improvement
PULMICORT®TURBOHALER
Prophylaxis of asthma
▶BY INHALATION OF POWDER
▶Child 5–11 years: 100 – 400 micrograms twice daily, dose
to be adjusted as necessary
▶Child 12–17 years: 100 – 800 micrograms twice daily, dose
to be adjusted as necessary
Alternative in mild to moderate asthma, for patients
previously stabilised on a twice daily dose
▶BY INHALATION OF POWDER
▶Child 5–11 years: 200 – 400 micrograms once daily, to be
taken in the evening
▶Child 12–17 years: 200 – 400 micrograms once daily (max.
per dose 800 micrograms), to be taken in the evening
POTENCY
▶Dose adjustments may be required for some inhaler
devices, see under individual preparations.

lUNLICENSED USEPulmicort®nebuliser solutionnot
licensed for use in children under 3 months; not licensed
for use in bronchopulmonary dysplasia.


lINTERACTIONS→Appendix 1 : corticosteroids


lDIRECTIONS FOR ADMINISTRATIONBudesonide nebuliser
suspension is not suitable for use in ultrasonic nebulisers.


lPATIENT AND CARER ADVICEWith high doses, a steroid
card should be supplied. Patients or carers should be given


advice on how to administer budesonide dry powder
inhaler and nebuliser suspension.
Medicines for Children leaflet: Budesonide inhaler for asthma
prevention (prophylaxis)www.medicinesforchildren.org.uk/
budesonide-inhaler-asthma-prevention-prophylaxis
BUDELIN NOVOLIZER®Patients or carers should be given
advice on adminstration ofBudelin Novolizer®.

lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Inhalation powder
CAUTIONARY AND ADVISORY LABELS8, 10
▶Budelin Novolizer(Meda Pharmaceuticals Ltd)
Budesonide 200 microgram per 1 doseBudelin Novolizer
200 micrograms/dose inhalation powder| 100 doseP£ 14. 86
Budelin Novolizer 200 micrograms/dose inhalation powder refill|
100 doseP£ 9. 59
▶Easyhaler (budesonide)(Orion Pharma (UK) Ltd)
Budesonide 100 microgram per 1 doseEasyhaler Budesonide
100 micrograms/dose dry powder inhaler| 200 doseP£ 8. 86 DT =
£ 14. 25
Budesonide 200 microgram per 1 doseEasyhaler Budesonide
200 micrograms/dose dry powder inhaler| 200 doseP£ 17. 71
Budesonide 400 microgram per 1 doseEasyhaler Budesonide
400 micrograms/dose dry powder inhaler| 100 doseP£ 17. 71
▶Pulmicort Turbohaler(AstraZeneca UK Ltd)
Budesonide 100 microgram per 1 dosePulmicort 100 Turbohaler
| 200 doseP£ 14. 25 DT = £ 14. 25
Budesonide 200 microgram per 1 dosePulmicort 200 Turbohaler
| 100 doseP£ 14. 25 DT = £ 14. 25
Budesonide 400 microgram per 1 dosePulmicort 400 Turbohaler
| 50 doseP£ 14. 25 DT = £ 14. 25
Nebuliser liquid
CAUTIONARY AND ADVISORY LABELS8, 10
▶Budesonide (Non-proprietary)
Budesonide 250 microgram per 1 mlBudesonide
500 micrograms/ 2 ml nebuliser liquid unit dose vials| 20 unit
doseP£ 30. 40 DT = £ 24. 86
Budesonide 500 microgram per 1 mlBudesonide 1 mg/ 2 ml
nebuliser liquid unit dose vials| 20 unit doseP£ 42. 41 DT =
£ 39. 00
▶Pulmicort Respules(AstraZeneca UK Ltd)
Budesonide 250 microgram per 1 mlPulmicort 0. 5 mg Respules|
20 unit doseP£ 31. 70 DT = £ 24. 86
Budesonide 500 microgram per 1 mlPulmicort 1 mg Respules|
20 unit doseP£ 48. 00 DT = £ 39. 00

Budesonide with formoterol 08-Feb-2018


The properties listed below are those particular to the
combination only. For the properties of the components
please consider, budesonide p. 160 , formoterol fumarate
p. 154.

lINDICATIONS AND DOSE
SYMBICORT 100/6 TURBOHALER®
Asthma, maintenance therapy
▶BY INHALATION OF POWDER
▶Child 6–17 years:Initially 1 – 2 puffs twice daily; reduced
to 1 puff daily, dose reduced only if control is
maintained
Asthma, maintenance and reliever therapy
▶BY INHALATION OF POWDER
▶Child 12–17 years:Maintenance 2 puffs daily in
1 – 2 divided doses; 1 puff as required for relief of
symptoms, increased if necessary up to 6 puffs as
required, max. 8 puffs per day; up to 12 puffs daily can
be used for a limited time but medical assessment is
recommended continued→

BNFC 2018 – 2019 Airways disease, obstructive 161


Respiratory system

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